[HTML][HTML] How do adenosine A2A receptors regulate motor function?
A Mori - Parkinsonism & related disorders, 2020 - Elsevier
… NoGo signals via enhancement of GABAergic synaptic transmission to the GPe. … transmission,
is exerted by opposing presynaptic control of GABA release by A 2A receptors on striatal …
is exerted by opposing presynaptic control of GABA release by A 2A receptors on striatal …
[HTML][HTML] Adjusting the brakes to adjust neuronal activity: Adenosinergic modulation of GABAergic transmission
AM Sebastião, JA Ribeiro - Neuropharmacology, 2023 - Elsevier
… Our understanding on the ways adenosine uses to modulate synapses, circuits, and brain
… However, except for A 2A receptors, whose actions upon GABAergic neurons of the striatum …
… However, except for A 2A receptors, whose actions upon GABAergic neurons of the striatum …
[HTML][HTML] Presynaptic adenosine receptor heteromers as key modulators of glutamatergic and dopaminergic neurotransmission in the striatum
… A 2A RD 2 R heteromers localized in the GABAergic striatal … Although the adenosine receptor
heteromers are proposed to … down-regulation of A 1 Rs in the cortex and striatum and up-…
heteromers are proposed to … down-regulation of A 1 Rs in the cortex and striatum and up-…
Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson's Disease
FQ Gonçalves, FC Matheus, HB Silva, JI Real… - Molecular …, 2023 - Springer
… such as glutamate or GABA from synaptosomes reaches a near maximal … function to these
synaptic P2R in the control of glutamatergic synaptic transmission or plasticity in the striatum…
synaptic P2R in the control of glutamatergic synaptic transmission or plasticity in the striatum…
[HTML][HTML] Pharmacological interactions between adenosine A2A receptor antagonists and different neurotransmitter systems
A Pinna, M Serra, J Marongiu, M Morelli - Parkinsonism & Related …, 2020 - Elsevier
… of the striatal indirect pathway [13]. In addition, a critical … in the regulation of synaptic
transmission and plasticity [46]. mGlu … during the release of GABA and glutamate from …
transmission and plasticity [46]. mGlu … during the release of GABA and glutamate from …
Adenosine receptors in neuropsychiatric disorders: fine regulators of neurotransmission and potential therapeutic targets
… protein density and increased A 2A ARs in the striatum and … A 2A ARs influence BDNF
effects on GABAergic transmission, … AMPA receptor-mediated synaptic transmission [69]. …
effects on GABAergic transmission, … AMPA receptor-mediated synaptic transmission [69]. …
Convergence of adenosine and GABA signaling for synapse stabilization during development
F Gomez-Castro, S Zappettini, JC Pressey, CG Silva… - Science, 2021 - science.org
… A 2A Rs act as detectors of active GABAergic synapses releasing GABA, adenosine triphosphate,
and adenosine to regulate … of synaptic transmission, the activation of either A 2A Rs or …
and adenosine to regulate … of synaptic transmission, the activation of either A 2A Rs or …
… together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA …
DO Borroto-Escuela, L Ferraro, S Beggiato… - Pharmacological …, 2021 - Springer
… role of adenosine A2A receptor (A2AR) and striatal-enriched protein tyrosine phosphatase
(STEP) interactions in the striatal-pallidal GABA … regulated by the dorsal striatal-pallidal GABA …
(STEP) interactions in the striatal-pallidal GABA … regulated by the dorsal striatal-pallidal GABA …
[HTML][HTML] Striatal astrocytic A2A-D2 receptor-receptor interactions and their role in neuropsychiatric disorders
… , is given by adenosine A2A and dopamine D2 receptors on the … in synaptic transmission
and co-actors with neurons in the brain … regulate NMDA-mediated firing in striatopallidal GABA …
and co-actors with neurons in the brain … regulate NMDA-mediated firing in striatopallidal GABA …
Retrograde adenosine/A2A receptor signaling facilitates excitatory synaptic transmission and seizures
… Here, we identified adenosine/A 2A receptor (A 2A R… synaptic inputs, a BDNF/TrkB-dependent
form of plasticity that facilitates seizures. Postsynaptic TrkB activation released adenosine …
form of plasticity that facilitates seizures. Postsynaptic TrkB activation released adenosine …