Cerebral microcirculation, perivascular unit, and glymphatic system: role of aquaporin-4 as the gatekeeper for water homeostasis
J Szczygielski, M Kopańska, A Wysocka… - Frontiers in …, 2021 - frontiersin.org
… permeability through the blood-brain barrier but also regulates … research developed, the
various tasks regarding global … seems to be crucial for the BBB integrity (122, 123). But even if …
various tasks regarding global … seems to be crucial for the BBB integrity (122, 123). But even if …
[HTML][HTML] Aquaporin-4 in glymphatic system, and its implication for central nervous system disorders
S Peng, J Liu, C Liang, L Yang, G Wang - Neurobiology of Disease, 2023 - Elsevier
… It has been suggested that the blood-brain barrier may not be fully developed in the anterior
… play a critical role in maintaining the integrity of the blood-brain barrier, removing hematoma …
… play a critical role in maintaining the integrity of the blood-brain barrier, removing hematoma …
[HTML][HTML] Upregulation of AQP4 improves blood–brain barrier integrity and Perihematomal edema following intracerebral hemorrhage
… ; GFAP and S100-beta for activated astrocytes; aquaporin-4; and CD31 for endothelial cells.
… it maintains the BBB's structural integrity to suppress the development of the PHE and can …
… it maintains the BBB's structural integrity to suppress the development of the PHE and can …
Protective effects of aquaporin-4 deficiency on longer-term neurological outcomes in a mouse model
X Liu, Y Xie, X Wan, J Wu, Z Fan, L Yang - Neurochemical Research, 2021 - Springer
… to blood–brain barrier (BBB) integrity and amyloid-β clearance. The inflammation of cerebral
… The occurrence and development of neuroinflammation further lead to vascular damage …
… The occurrence and development of neuroinflammation further lead to vascular damage …
… hematoma expansion induced by hypertension and hyperglycemia and blood–brain barrier disruption in mice and its possible mechanism: Role of Aquaporin-4 and …
H Chu, Z Gao, C Huang, J Dong, Y Tang, Q Dong - Neuroscience Bulletin, 2020 - Springer
… Moreover, AQP4 regulates the functions of astrocytes due to its distribution, … integrity [44].
It has been emphasized that AQP4 is critical for the maintenance of BBB integrity in developing …
It has been emphasized that AQP4 is critical for the maintenance of BBB integrity in developing …
Mesenchymal stem cells attenuated blood-brain barrier disruption via downregulation of aquaporin-4 expression in EAE mice
… on blood-brain barrier in multiple sclerosis remains unclear. Here, we investigated whether
mesenchymal stem cells transplantation protected blood-brain barrier integrity … , developing …
mesenchymal stem cells transplantation protected blood-brain barrier integrity … , developing …
Aquaporin-4 expression in the human choroid plexus
F Deffner, C Gleiser, U Mattheus, A Wagner… - Cellular and Molecular …, 2022 - Springer
… Besides the blood–brain barrier, there is an outer and inner blood-cerebrospinal fluid barrier
(… The QIAxcel Advanced System (Qiagen) was used to determine both RNA integrity and …
(… The QIAxcel Advanced System (Qiagen) was used to determine both RNA integrity and …
[HTML][HTML] The role of aquaporin 4 (AQP4) in spinal cord injury
QL Pan, FX Lin, N Liu, RC Chen - Biomedicine & Pharmacotherapy, 2022 - Elsevier
… the blood-brain barrier (BBB) in both wild-type and AQP-4-deficient mice, while cerebral water
… hypoglycemia in mice, ensuring the maintenance of the integrity of the BBB. TNF-α and IL-…
… hypoglycemia in mice, ensuring the maintenance of the integrity of the BBB. TNF-α and IL-…
Circulating Aquaporin-4 as A biomarker of early neurological improvement in stroke patients: A pilot study
L Ramiro, A Simats, A Penalba, A Garcia-Tornel… - Neuroscience …, 2020 - Elsevier
… ROC curve of the multivariate regression models developed to predict improvement at 48 h
… play a role in brain-blood barrier (BBB) integrity [12,13]. However, recent research pointed …
… play a role in brain-blood barrier (BBB) integrity [12,13]. However, recent research pointed …
Purified IgG from aquaporin-4 neuromyelitis optica spectrum disorder patients alters blood-brain barrier permeability
A Cobo-Calvo, A Ruiz, C Richard, S Blondel… - PLoS …, 2020 - journals.plos.org
… blood-brain barrier (BBB) breakdown is considered one of the key steps for the development
… To test the integrity of the barrier, [14C] sucrose was added in the upper compartment at the …
… To test the integrity of the barrier, [14C] sucrose was added in the upper compartment at the …