[HTML][HTML] Mechanism of membrane fusion: Interplay of lipid and peptide

A Joardar, GP Pattnaik, H Chakraborty - The Journal of Membrane Biology, 2022 - Springer
… Further, vacuoles fusion takes time of minute while synaptic vesicle fusion takes place …
fusion) (Jahn et al. 2003). In addition, the fusogens are specific for a specific membrane fusion

[PDF][PDF] Target membrane cholesterol modulates single influenza virus membrane fusion efficiency but not rate

KN Liu, SG Boxer - Biophysical journal, 2020 - cell.com
… of dye-labeled lipids to the viral membrane, we tether virions to lipid-labeled target … IAV
membrane fusion events. Through this approach, we find that cholesterol in the target membrane

[PDF][PDF] Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry

J Lee, AJB Kreutzberger, L Odongo, EA Nelson… - Biophysical …, 2021 - cell.com
… that cholesterol-TM interactions affect structural features of GP2 thereby facilitating fusion
and … as part of EBOV treatments due to their ability to lower cholesterol in the viral membrane. …

[PDF][PDF] Single-virus content-mixing assay reveals cholesterol-enhanced influenza membrane fusion efficiency

KN Liu, SG Boxer - Biophysical Journal, 2021 - cell.com
… content-loss events between IAV and target vesicles of varying cholesterol compositions.
We show that target membrane cholesterol increases the efficiency of IAV content mixing and …

[HTML][HTML] Membranotropic and biological activities of the membrane fusion peptides from SARS-CoV spike glycoprotein: The importance of the complete internal fusion …

LGM Basso, AE Zeraik, AP Felizatti… - Biochimica et Biophysica …, 2021 - Elsevier
membrane fusion peptide sequences from the SARS-CoV S glycoprotein (FP1, FP2, and cIFP)
with model and biological cell membranes… permeabilization and membrane fusion activity …

Coronavirus membrane fusion mechanism offers a potential target for antiviral development

T Tang, M Bidon, JA Jaimes, GR Whittaker, S Daniel - Antiviral research, 2020 - Elsevier
… the role of the CoV spike protein in mediating fusion of the viral and host cell membranes, …
-CoV-2, and suggest that the fusion mechanism be investigated as a potential antiviral target. …

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

R Zang, JB Case, E Yutuc, X Ma… - Proceedings of the …, 2020 - National Acad Sciences
… Internalized 25HC accumulates in the late endosomes and potentially restricts SARS-CoV-2
spike protein catalyzed membrane fusion via blockade of cholesterol export. Our results …

[HTML][HTML] Viral membrane fusion and the transmembrane domain

CT Barrett, RE Dutch - Viruses, 2020 - mdpi.com
… how fusion proteins facilitate membrane merging is relatively conserved. Membrane fusion
promoted by viral fusion … by factors within the fusion protein or viral attachment protein ligand. …

Mechanisms of SNARE proteins in membrane fusion

R Jahn, DC Cafiso, LK Tamm - Nature Reviews Molecular Cell Biology, 2024 - nature.com
… in addition to viral membrane fusion, our understanding of SNARE-mediated fusion is most
advanced. … membrane fusion. Experimentally, it is still difficult to access the transition states of …

Supported lipid bilayer formation: beyond vesicle fusion

JA Jackman, NJ Cho - Langmuir, 2020 - ACS Publications
… While the vesicle fusion technique … vesicle fusion alone and view the SALB and bicelle
methods as emerging options that complement, and in some cases go beyond, the vesicle fusion