Binding mode of SARS-CoV-2 fusion peptide to human cellular membrane
… role in the initial penetration of the virus into the host cell membrane, followed by the fusion of
the two membranes… Structures and mechanisms of viral membrane fusion proteins: multiple …
the two membranes… Structures and mechanisms of viral membrane fusion proteins: multiple …
TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine
… Finally, we monitored cholesterol with a newly developed probe for cholesterol: GRAM 1b (…
properties of cellular membranes; in their absence, more cholesterol becomes accessible on …
properties of cellular membranes; in their absence, more cholesterol becomes accessible on …
The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER–Golgi membrane contact sites
Y Wakana, K Hayashi, T Nemoto, C Watanabe… - Journal of Cell …, 2020 - rupress.org
… cholesterol sensing–defective mutants. Altogether, our findings reveal a new role for SCAP
under cholesterol-… CARTS biogenesis via ER–Golgi MCSs, depending on the ER cholesterol. …
under cholesterol-… CARTS biogenesis via ER–Golgi MCSs, depending on the ER cholesterol. …
Cholesterol determines the cytosolic entry and seeded aggregation of tau
… Depletion of the cholesterol transporter Niemann-Pick type C1 or extraction of membrane
cholesterol renders neurons highly permissive to tau entry and potentiates seeding even at low …
cholesterol renders neurons highly permissive to tau entry and potentiates seeding even at low …
Effect of cholesterol on the structure of networked water at the surface of a model lipid membrane
… , we investigated the effect of membrane cholesterol level on the structure of organized …
and a model lipid membrane. Irrespective of membrane cholesterol content, interfacial water …
and a model lipid membrane. Irrespective of membrane cholesterol content, interfacial water …
Increased efficiency of charge-mediated fusion in polymer/lipid hybrid membranes
N Marušič, L Otrin, J Rauchhaus… - Proceedings of the …, 2022 - National Acad Sciences
… In eukaryotic cells, membrane fusion by SNARE proteins (1) plays a crucial role in various
cellular functions, such as exo- and endocytosis, membrane remodeling, cell division, signal …
cellular functions, such as exo- and endocytosis, membrane remodeling, cell division, signal …
Insight into the siRNA transmembrane delivery—from cholesterol conjugating to tagging
Y Zheng, W Tai - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
… By the comparison of the virus's membrane fusion and the aforementioned examples, we
hypothesized that two pre-requirements are essential for transmembrane siRNA delivery: (a) …
hypothesized that two pre-requirements are essential for transmembrane siRNA delivery: (a) …
Strikingly different roles of SARS-CoV-2 fusion peptides uncovered by neutron scattering
A Santamaria, KC Batchu, O Matsarskaia… - Journal of the …, 2022 - ACS Publications
… , synthetic model membranes, as well as biomimetic plasma membrane (PM) with … cholesterol
composition were studied. Depleting membrane cholesterol inhibits viral membrane fusion …
composition were studied. Depleting membrane cholesterol inhibits viral membrane fusion …
[HTML][HTML] Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol
… To optimise vesicle fusion, lipids were deposited at a concentration of 0.1 mg mL −1 in
the presence of 2 mM CaCl 2 [38,39]; freshly tip-sonicated lipids were mixed with an equal …
the presence of 2 mM CaCl 2 [38,39]; freshly tip-sonicated lipids were mixed with an equal …
Calcium-triggered fusion of lipid membranes is enabled by amphiphilic nanoparticles
MA Tahir, ZP Guven, LR Arriaga… - Proceedings of the …, 2020 - National Acad Sciences
… Lipid membrane fusion is an essential process for a number of critical biological functions. …
modulate membrane fusion and equivalently prime lipid membranes for calcium-triggered …
modulate membrane fusion and equivalently prime lipid membranes for calcium-triggered …