[HTML][HTML] Lipid accumulation controls the balance between surface connection and scission of caveolae

M Hubert, E Larsson, NVG Vegesna, M Ahnlund… - Elife, 2020 - elifesciences.org
… the plasma membrane (PM) that undergo scission and fusion at … into the cell PM via membrane
fusion and studied their acute … surface, whereas cholesterol and glycosphingolipids drive …

[HTML][HTML] Sterols, oxysterols, and accessible cholesterol: signalling for homeostasis, in immunity and during development

WJ Griffiths, Y Wang - Frontiers in Physiology, 2021 - frontiersin.org
Membrane fusion proceeds and results in release of viral RNA into the cytoplasm. … membrane
fusion can be mediated by reducing accessible cholesterol at both the plasma membrane

Molecular mechanisms for ABCA1-mediated cholesterol efflux

L Chen, ZW Zhao, PH Zeng, YJ Zhou, WJ Yin - Cell Cycle, 2022 - Taylor & Francis
… Its major function is to mediate the transport of free cholesterol (FC) and phospholipids from
… that ABCA1-dependent cholesterol efflux plays a central role in blocking the transformation …

[HTML][HTML] Possible mechanisms of cholesterol elevation aggravating COVID-19

Y Tang, L Hu, Y Liu, B Zhou, X Qin, J Ye… - … journal of medical …, 2021 - ncbi.nlm.nih.gov
Cholesterol in the virus may interact with the fusion protein … focused on cholesterol
dependence during membrane fusion, but it should also be considered whether cholesterol binds to …

TMEM135 regulates primary ciliogenesis through modulation of intracellular cholesterol distribution

Y Maharjan, JN Lee, SA Kwak, RK Dutta, C Park… - EMBO …, 2020 - embopress.org
… in the lysosomal compartment disrupts the normal cholesterol distribution in other … that
affect vesicle fusion events 37. Furthermore, it is well known that the coordinated function of …

Engineered extracellular vesicles with synthetic lipids via membrane fusion to establish efficient gene delivery

YY Jhan, D Prasca-Chamorro, GP Zuniga… - International journal of …, 2020 - Elsevier
… incorporation of lipids to extracellular vesicles, we conducted membrane composition
analysis to quantitatively evaluate the efficiency of membrane fusion. Osteikoetxea, X., et al. …

[HTML][HTML] Generating membrane curvature at the nuclear pore: A lipid point of view

BWA Peeters, ACA Piët, M Fornerod - Cells, 2022 - mdpi.com
… is also necessary for the completion steps of fusion [83]. The hypothesis is that cholesterol
facilitates membrane fusion by lowering the energetic cost for curved fusion intermediates, …

Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain

G Vardar, A Salazar-Lázaro, S Zobel, T Trimbuch… - Elife, 2022 - elifesciences.org
… might actively regulate vesicle fusion by reducing the energy barrier for membrane merger.
… STX1A plays additional roles in vesicle fusion to facilitate the membrane merger through its …

Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets

J Kopecka, P Trouillas, AČ Gašparović, E Gazzano… - Drug resistance …, 2020 - Elsevier
… This feature, along with the increased levels of cholesterol, decrease membrane fluidity,
alter the spatial organization of membrane nano- and micro-domains, interact with …

Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters

P Ridone, E Pandzic, M Vassalli, CD Cox… - Journal of General …, 2020 - rupress.org
membrane localization and organization. Using a PIEZO1-GFP fusion protein, we investigated
whether cholesterol … ) and disruption of membrane cholesterol organization by dynasore …