… are of great importance to therapies targeting inflammation due to their critical role in
regulating inflammation. In many bacterial infections, pathogens activate NLRP3-based …

… factor to protect host from bacterial infection, while how it elicits this role is unclear. In the …
In the present study, we examined the role of β-catenin on NLRP3 inflammasome activation …

… of the microbiome and its bacterial components on NLRP3 inflammasome activation and …
bacterial infections must be taken into account in future studies involving NLRP3 inflammasome…

… sensors, which plays a role in the detection of cytosolic infections or disruption. The NLR-…
against various bacterial infections by detecting bacterial flagellin or two bacterial type III …

… -canonical NLRP3 inflammasome activation occurs upon Gram-negative bacteria infection or
… confirmed the crucial role of mitochondria in regulating NLRP3 inflammasome, it raised two …

… infection shows IL-1β release via the caspase-8–ASC association [19]. Overall, the activation
of the NLRP3 inflammasome … There are over 500 different types of bacteria in our intestine. …

… Importantly, both the NAIP/NLRC4 and NLRP3 inflammasomes played a functional role in
… The NLRP3 inflammasome can be activated by diverse stimuli during bacterial infection, …

… role for NAIP/NLRC4 and NLRP3 inflammasome activation has been demonstrated upon S.
Typhimurium infection … ” to preserve inflammasome activation during bacterial infection in the …

… role of mitochondrial oxidative stress in bacterial survival, IFN-I secretion and NLRP3
inflammasome activation in MAB-infected … resulting in enhanced NLRP3 inflammasome-mediated …

… in response to a variety of pathogenic bacterial infections and danger signals [60]. Recent
… caspase-8 plays an opposing role in NLRP3 inflammasome activation, but our knowledge …