A comprehensive review of scaffolding methods in genome assembly
J Luo, Y Wei, M Lyu, Z Wu, X Liu, H Luo… - Briefings in …, 2021 - academic.oup.com
… in related reference genome to analyze DNA methylation, … reads that are in close proximity
in the 3-D space. The number of Hi-… WiseScaffolder [68] uses a manual intervention model to …
in the 3-D space. The number of Hi-… WiseScaffolder [68] uses a manual intervention model to …
Compositional structure of the genome: a review
P Bernaola-Galván, P Carpena, C Gómez-Martín… - Biology, 2023 - mdpi.com
… structure of DNA, which plays a vital role in determining its … composition has been related
to important genome features such as the so-called genomic code [9], the 3-D structure of DNA […
to important genome features such as the so-called genomic code [9], the 3-D structure of DNA […
Amplification editing enables efficient and precise duplication of DNA from short sequence to megabase and chromosomal scale
R Zhang, Z He, Y Shi, X Sun, X Chen, G Wang… - Cell, 2024 - cell.com
… Here, we develop a genome editing tool named … (Figures 3D–3G). To gain an overall
perspective of the outcomes for … Initial analysis involved gel extraction and Sanger sequencing to …
perspective of the outcomes for … Initial analysis involved gel extraction and Sanger sequencing to …
[PDF][PDF] Algorithmic approaches to biological sequence analysis generate new tools for the study of genome structure and function.
L Matej - is.muni.cz
… biologists in analyzing genome evolution and 3-D structure? … -mer hashing-based short
sequence alignment algorithm; an … that non-B DNA might play some role in their life cycle. Having …
sequence alignment algorithm; an … that non-B DNA might play some role in their life cycle. Having …
Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment
T Zhang, T Tian, R Zhou, S Li, W Ma, Y Zhang, N Liu… - Nature protocols, 2020 - nature.com
… replacing a short sequence of a single DNA strand by an … type and modification method,
which takes from 2 h to 3 d. … and is suitable for specialists involved in DNA nanomaterials and …
which takes from 2 h to 3 d. … and is suitable for specialists involved in DNA nanomaterials and …
The “genomic code”: DNA pervasively moulds chromatin structures leaving no room for “Junk”
G Bernardi - Life, 2021 - mdpi.com
… can be distinguished on the basis of short-sequence profiles, an important point because …
in the experiments presented, based as it is on the role of DNA sequences in the moulding of …
in the experiments presented, based as it is on the role of DNA sequences in the moulding of …
[HTML][HTML] Bioinformatics approach for prediction and analysis of the Non-Structural Protein 4B (NSP4B) of the Zika virus
… for full-length 3-D protein structure predictions of NSP4B, … replication complex and its
participation in the localization of … The nonstructural proteins carry out critical tasks in genome …
participation in the localization of … The nonstructural proteins carry out critical tasks in genome …
dCas9-based gene editing for cleavage-free genomic knock-in of long sequences
… enzymes—could help understand such involvement. Mining additional SSAPs from nature
… Briefly, we harvested the HEK293T cells 3 d after transfection. The genomic DNA was size-…
… Briefly, we harvested the HEK293T cells 3 d after transfection. The genomic DNA was size-…
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
L Zhou, Q Qiu, Q Zhou, J Li, M Yu, K Li, L Xu… - Nature …, 2022 - nature.com
… papillomavirus (HPV) DNA into the human genome is considered as a … Additionally, the
involved region on the host genome was … The trimmed short sequence reads were aligned to the …
involved region on the host genome was … The trimmed short sequence reads were aligned to the …
Sequential requirements for distinct Polθ domains during theta-mediated end joining
C Fijen, LD Beckham, D Terino, Y Li, DA Ramsden… - Molecular Cell, 2024 - cell.com
… DNA polymerase θ (Polθ) plays a central role in a DNA … TMEJ functions by pairing short-sequence
“microhomologies… can compromise genome integrity and lead to genomic instability …
“microhomologies… can compromise genome integrity and lead to genomic instability …