[HTML][HTML] Standing on the shoulders of mice

K Medetgul-Ernar, MM Davis - Immunity, 2022 - cell.com
… antibody and T cell receptor diversity, major histocompatibility complex (MHC) restriction, and
… For the superantigen results, this early expression was probably due to the abundance of …

[PDF][PDF] How do extracellular membrane-associated proteins stand erect and signal?

S Lankipalli, UA Ramagopal - scholar.archive.org
… cells that interact with peptideloaded major histocompatibility … DR1 in complex with
superantigen Staphylococcus aureus … with CD4 (D1-D2) revealed that the CD4 binding region is in …

Dangerous Proteins and Where to Find Them-Structural and functional studies of bacterial and viral proteins interacting with human immune receptors in health and …

S Uzuncayir - 2022 - portal.research.lu.se
… are presented by major histocompatibility complex II (MHCII) to … and functional data of
superantigens, and the superantigen-… TRBV of TCRs bind presumably the NTD/RBD domain of the …

From nutritional support to innovative vaccines: Approaches to bolster the immune response to respiratory infection

S Hong - 2024 - search.proquest.com
… viral peptides via their major histocompatibility complex (MHC) class I molecules to activate
… with recombinant SARS-CoV-2 receptor-binding domain protein resulted in the attenuation …

[HTML][HTML] Analysis of enterotoxigenic effect of Staphylococcus aureus and Staphylococcus epidermidis enterotoxins C and L on mice

A Tabiś, M Gonet, J Schubert, A Miazek, M Nowak… - Microbiological …, 2022 - Elsevier
superantigenic activity, that is, they can simultaneously bind to a major histocompatibility
complex class II (MHC II… the peptide binding groove and to a Vβ or rarely to Vα region within the …

Structural biology of SARS-CoV-2 accessory proteins

DC Briggs, L Kandler, L Schmidt, G Santoni… - Crystallography …, 2023 - Taylor & Francis
Major Histocompatibility Complex (MHC) class I pathway, by inhibiting NLR Family CARD
Domain … to pathogens, as is seen in superantigens, proteins that subvert the hosts immune …

Toward understanding how staphylococcal protein A inhibits IgG-mediated phagocytosis

AR Cruz, AEH Bentlage, R Blonk… - The Journal of …, 2022 - journals.aai.org
… -binding domains. Although SpA-WT is composed of five different Ig-binding domains, SpA-B
contains a single B domain… on IgG-FcRn binding when IgGs were in solution. We measured …

[HTML][HTML] Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4

J Zeng, Y Fang, Z Zhang, Z Lv, X Wang, Q Huang… - Oncogene, 2024 - nature.com
… induces IL-2 expression by cross-linking the major histocompatibility complex class II (MHC
II) on … In summary, a lipid solution comprising an ionizable lipid, cholesterol, a phospholipid (…

Novel bioinformatics tools for epitope-based peptide vaccine design

T Whalley - 2022 - orca.cardiff.ac.uk
… on the major histocompatibility complex (pMHC). TCR-pMHC interaction is critical to vaccination.
In this thesis I will discuss three … nucleotide-binding oligomerization domain NSP1-16 …

[HTML][HTML] Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis

S Zhang, Q Xu, L Shi, S Li, W Wang, Q Wang… - … and Targeted Therapy, 2023 - nature.com
… -type lectin receptors (CLRs) and nucleic acid sensors. The recognition upregulates both
major histocompatibility complexes (MHC I and IIdomain to interact with β 2 -domain of MHC II, …