… binds to peptide-loaded major histocompatibility complex (pMHC… the adaptive response,
the solution is to render down … has a stabilizing effect on this region that is not captured in our …

… of Major Histocompatibility Complex class II, superantigen and T-cell receptor. Superantigens
directly interact with MHC-II … overall structural fold comprising of two major protein domains: …

… domain is responsible for binding to the diverse major … superantigen, can elicit massive T
cell activation through simultaneous binding to major histocompatibility complex (MHC) class II …

… variable domains bind antigens and the constant domains … The ability of superantigens to
evoke such a strong immune … to bind both the Major Histocompatibility complex (MHC) class …

… polymorphic major histocompatibility complex class I (MHC-I) … for MHC-I peptide binding motif
prediction that learns their … monitor how MHC-I polymorphisms alter the binding motifs, and …

… two binding sites: one in the OB domain for the MHC class II α chain and the other in the β-grasp
domain for … mg/mL SSL7 or SSL11, followed by transfer of the protein solution to a vial of …

… aureus consists of at least 26 different paralogues that function by cross-linking major
histocompatibility complex (MHC) class II molecules with the variable region of the T cell receptor (…

… superantigen assists the colonization of S. aureus [4, 5]. TSST-1 of S. aureus binds to major
histocompatibility complex II (MHC II) at a … These toxins (superantigens such as TSST-1) are …

… Patients with TRBV11-2 expansion shared HLA class I alleles … -2 (Vβ21.3) strongly interact
with the superantigen-like motif … favor instead an exposure to the solution. Thus, the sequence …

… glycolytic enzyme was shown to bind to domains 1-2 and 8 of the … superantigens overstimulate
T cells by binding nonspecifically to the major histocompatibility complex class II (MHC II…