… The ArdA DNA-mimic antirestriction proteins inhibit type I … The ArdA specificity to DNA
methylation sites recognized by … of the EcoKI RMI system with a dimer of the antirestriction protein …

… The anti-restriction protein ArdA belongs to the DNA mimic … In other words, DNA methylation
protects it from the restrictive … of the type I RM enzyme EcoKI, indicating that the KlcA protein …

… A second copy of S gene is on a plasmid. D) … of epigenetic DNA methylation decreases,
while this Type IV system … evolved anti-restriction features, such as solitary methyltransferases …

… proposed that epigenetic memory systems have numerous potential applications in synthetic
biology, including life biosensors, death switches or induction systems for industrial protein …

… several other DNA mimic antirestriction proteins, overcomes … coli AB1157 carrying a genomic
copy of type I EcoKI R–M … binds to BrxX, a DNA methyltransferase, which is responsible for …

… ArdA is a DNA mimic (46); ArdB inhibits Type IR–M in vivo … on AB1157ΔhsdM and thus
lacked EcoKI methylation. … this EcoKI site is required for anti-restriction activity, we introduced …

… was used to investigate DNA methyltransferases M.BceJIII and … Thus, we can separate
copy-number effects from effects of … MG1655, and likely expresses the Type I enzyme EcoKI. …

… with the DNA-mimicking anti-restriction proteins Ocr and … the M-domain adds further structural
information and improves understanding of the mechanism of DNA methylation by the type …

… DNA methylation is ubiquitously found in all three domains of … of this ORF to mimic synthetic
construct DraRI reported earlier [… Another anti-restriction strategy is restriction site avoidance, …

… ) and a DNA methyltransferase (MTase). Most entering … levels of the R–M proteins were
associated with reduced … activities from a single-copy R–M system is operating very close to the …