… 50 of saffron extracts in normal cells, its toxicity against non-cancerous cells is low and its use
… Saffron and its components have low toxicity and can be even considered nontoxic in oral …

… cancer. These findings suggest that saffron’s compounds could have potent cancer-…
and antitumor activity with selective toxicity against cancer cells, without affecting the normal …

… obtained from the dried stigmas of Crocus sativus L. flowers [1,2]. … , the main saffron component,
effect on invasive cancer cells, MDA… Saffron and its active components have a key role in …

… Crocus sativus L. is a perennial underground corm that … measure the possible toxic effect of
the samples on RBL-2H3 cells as … in HaCaT normal cells and Huh7 cancer cells according to …

… is the most expensive dietary spice and is derived from the stigmas of Crocus sativus L. …
about subchronic and chronic toxic effects of saffron and its main constituents, so the design …

… significance of saffron in osteosarcoma cancer cells. … but these agents often cause several
side effects by their high toxicity. [4… the phytochemical constituents of Safranbolu saffron and its …

… Outcomes of this study revealed safranal as a low-toxic compound in acute … saffron, Crocus
sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal …

… constituent of Crocus sativus L. stigmas, primarily responsible for the pharmacologic activity
of saffron … mL did not demonstrate any toxicity to the normal thyroid (PCCL3) cells [97]. CRCs …

… effects of saffron and its constituents in CRC cell lines with … assessed saffron and its major
components on HCT116 cells. … wherein HCT116 cells with different p53 (a tumor suppressor …

… trials and safety evaluation should be conducted to assess the clinical value and effective
dose of saffron and to elucidate the dose-response and dose-toxicity relationships of the active …