Transient receptor potential vanilloid 1 antagonism in neuroinflammation, neuroprotection and epigenetic regulation: Potential therapeutic implications for severe …

A Escelsior, B Sterlini, MB Murri, P Valente… - Psychiatric …, 2020 - journals.lww.com
Transient receptor potential vanilloid 1 (TRPV1) is a polymodal cation channel gated by a
large array of chemical and physical stimuli and distributed across different brain regions on …

In vitro characterization of the thermoneutral transient receptor potential vanilloid-1 (TRPV1) inhibitor GRTE16523

N Damann, G Bahrenberg, H Stockhausen… - European Journal of …, 2020 - Elsevier
… buffer A at room temperature and protected from light. An amount of … The relative humidity
was 40–68% for the duration of the … monitored by Maccine throughout the duration of the study. …

Capsaicin, the vanilloid receptor TRPV1 agonist in neuroprotection: mechanisms involved and significance

OME Abdel-Salam, G Mózsik - Neurochemical Research, 2023 - Springer
receptor or transient receptor potential cation channel … rats live longer and postponed the
onset of cerebral stroke. Until … or (TRPV1 stimulation) via antithrombotic action protects against

Role of the transient receptor potential vanilloid type 1 (TRPV1) in the regulation of nitric oxide release in wistar rat aorta

E Varela-López, L del Valle-Mondragón… - Oxidative Medicine …, 2021 - Wiley Online Library
… The transient receptor potential vanilloid type 1 (TRPV1) is a membrane structure that … 1 :
10 with 0.1 M NaOH before being analyzed. All samples were kept at -70C until the beginning

Activation of transient receptor potential vanilloid 1 ameliorates tau accumulation‐induced synaptic damage and cognitive dysfunction via autophagy enhancement

T Zhang, Y Tian, X Zheng, R Li, L Hu… - CNS Neuroscience …, 2024 - Wiley Online Library
… agonist of transient receptor potential vanilloid 1 (TRPV1). The … by which TRPV1 activation
protects neuronal functions by … 0.01%), but our treatment duration was much shorter (9 weeks …

The transient receptor potential channel vanilloid 1 is critical in innate airway epithelial responses to protease allergens

C Schiffers, M Hristova, A Habibovic… - American journal of …, 2020 - atsjournals.org
… The respiratory epithelium forms a protective barrier in the … under 1% isoflurane anesthesia
for a total duration of 1 hour, … of the transient receptor potential channel TRPV1 as a common …

[HTML][HTML] Transient receptor potential vanilloid subtype 1: potential role in infection, susceptibility, symptoms and treatment of COVID-19

F Liviero, M Campisi, P Mason, S Pavanello - Frontiers in Medicine, 2021 - frontiersin.org
… and duration of infection. Interestingly, treatment with TRPV-… TRPV-1 might therefore provide
a protective environment to … , by use of an ultra-potent TRPV1 agonist could modulate the …

Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel

W Long, M Fatehi, S Soni, R Panigrahi… - The Journal of …, 2020 - Wiley Online Library
… 25OHD and 1,25OHD are novel endogenous TRPV1 partial … added to the culture medium
at the start of activation. After 24 h, … , we determined that 25OHD prevents the PKC-mediated …

TRPV1 (transient receptor potential vanilloid 1) sensitization of skeletal muscle afferents in type 2 diabetic rats with hyperglycemia

R Ishizawa, HK Kim, N Hotta, GA Iwamoto… - …, 2021 - Am Heart Assoc
TRPV1 (transient receptor potential vanilloid 1)-induced cardiovascular responses in vivo
and muscle afferent discharge ex vivo in T2D rats. Additionally, TRPV1 … , TRPV1 agonist, in …

Transient receptor potential vanilloid 1: A potential therapeutic target for the treatment of osteoarthritis and rheumatoid arthritis

Z Liao, M Umar, X Huang, L Qin, G Xiao… - Cell …, 2024 - Wiley Online Library
… has indicated that the TRPV1 agonist capsaicin activates TRPV1 … GPX4 protects chondrocytes
from ferroptosis and reduces … of TRPV1 on different cell types of the joint during the onset