… whether physical interactions between menin and … inhibitor MI-503 [23] disrupts the
menin-KMT2A interaction that negatively influences downstream ATP production in breast cancer …

… Menin is tumor suppressor protein, mutated in multiple endocrine neoplasia type 1 … of menin
on NF-κB-mediated transactivation. Thus, the interaction of menin and RPA2 can inhibit the …

… of the pro-apoptotic protein Bim, thereby promoting apoptosis (… TNF-α can synergistically
inhibit apoptosis levels not only by … NF-κB activation and up-regulating the anti-apoptotic protein …

… Understanding the multifaceted interactions between NF-κB … . found that NF-κB acts as a
tumor suppressor in four ovarian cancer cell … This NF-κB-mediated effect correlates to decreased …

… PBX-MEIS1 protein-protein interaction is required for the induction of … downregulation via
NF-κB-mediated OCT-2 induction (Marin-Muller et al., 2013). In addition, the inhibition of miR-…

… can also inhibit survival signaling by inactivating the NF-κB … Consequently, NF-κB-mediated
differentiation or pro-… , inactive NF-κB is sequestered in the cytoplasm through its interaction …

… FOXOs are well-known as tumor suppressors and induce cell … to cancer progression, and
pharmacological CDK inhibition … study of membrane protein CD83-interacting proteins in cells …

… interaction between KMT2A/B and Menin drives derepression of bivalent MHC-I genes,
we utilized small molecule inhibitors … Menin has been reported to inhibit NF-κB p65-mediated …

… nuanced interactions between p53 and NF-κB could offer new … NF-κB-mediated anti-apoptotic
genes and the downregulation of … induces cell cycle arrest or tumour suppression, NF-κB …

… trans-represses ER functions that can proceed through protein-protein interaction or by … or
ER inhibitors drives NF-κB-mediated tumor progression by releasing NF-κB from the inhibitory …