Type IV secretion systems: advances in structure, function, and activation
… Upon binding of DNA or protein secretion substrates, how … poorly understood aspects of
type IV secretion. According to … of secretions associated with types II and III secretion systems, …
type IV secretion. According to … of secretions associated with types II and III secretion systems, …
Mechanisms of secretion and spreading of pathological tau protein
CA Brunello, M Merezhko, RL Uronen… - Cellular and Molecular …, 2020 - Springer
… that aim to reduce the cellular burden of aggregated proteins and also promote secretion of
tau … mechanisms involved in cell-to-cell transfer of tau, with a particular focus in tau secretion. …
tau … mechanisms involved in cell-to-cell transfer of tau, with a particular focus in tau secretion. …
Mechanisms controlling pancreatic islet cell function in insulin secretion
JE Campbell, CB Newgard - Nature reviews Molecular cell biology, 2021 - nature.com
… underlying mechanisms, particularly relating to the second or amplifying phase of this secretory
… a new perspective for the understanding of the β-cell failure that triggers type 2 diabetes. …
… a new perspective for the understanding of the β-cell failure that triggers type 2 diabetes. …
Contact-dependent interbacterial antagonism mediated by protein secretion machines
… or (ii) antibacterial protein toxins that rely on protein secretion apparatuses to facilitate their
contact-dependent delivery to target cells. Examples of contact-independent antibacterial …
contact-dependent delivery to target cells. Examples of contact-independent antibacterial …
Envelope stress responses defend against type six secretion system attacks independently of immunity proteins
… Although the exact underlying mechanisms for this protection require further investigation,
they might involve a healthy envelope providing a buffer of time to repair effector-mediated …
they might involve a healthy envelope providing a buffer of time to repair effector-mediated …
Exercise and type 2 diabetes
S Amanat, S Ghahri, A Dianatinasab… - Physical Exercise for …, 2020 - Springer
… underlying mechanisms is regulation of inflammatory cytokines production. Exercise may
directly reduce the inflammatory cytokines secretion… decrease urine protein excretion likely due …
directly reduce the inflammatory cytokines secretion… decrease urine protein excretion likely due …
Type 2 immunity in the skin and lungs
CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
… Th2 cells and innate lymphoid cells (ILC) produce and secrete type 2 cytokines such as IL-4…
type 2 immune components. The present review aims to highlight recent advances in type 2 …
type 2 immune components. The present review aims to highlight recent advances in type 2 …
Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria
… marcescens employs the T1SS HasDEF/TolC to secrete the heme-binding protein HasA, …
reported to be involved in the secretion of enterotoxin II from the periplasm into the extracellular …
reported to be involved in the secretion of enterotoxin II from the periplasm into the extracellular …
Emerging targets in type 2 diabetes and diabetic complications
S Demir, PP Nawroth, S Herzig… - Advanced …, 2021 - Wiley Online Library
… Senescence-associated secretory phenotype (SASP) which is shared in both type 2 diabetes
and … The exact underlying mechanisms that lead to metabolic memory remain elusive. …
and … The exact underlying mechanisms that lead to metabolic memory remain elusive. …
Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations
… Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. … an
underlying predisposition to deficient insulin secretion, which has a key role in the pathogenesis …
underlying predisposition to deficient insulin secretion, which has a key role in the pathogenesis …