Target therapy for BRAF mutated anaplastic thyroid cancer: a clinical and molecular study

TN da Silva, R Rodrigues, A Saramago… - European Journal of …, 2023 - academic.oup.com
… approved by the FDA for anaplastic thyroid cancer. Our study, in a … therapy and at clinical
resistance. This is the first European real-world study that shows the feasibility of this approach

[HTML][HTML] Advances and challenges in thyroid cancer: The interplay of genetic modulators, targeted therapies, and AI-driven approaches

S Bhattacharya, RK Mahato, S Singh, GK Bhatti… - Life Sciences, 2023 - Elsevier
… of thyroid carcinoma warrant a distinct approach. … therapy, have proven to be relatively
effective [3]. However, rare variants of thyroid carcinoma, such as anaplastic thyroid carcinoma, …

Pediatric thyroid cancer: recent developments

CE Cherella, AJ Wassner - … Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
… Other tumor types such as anaplastic thyroid carcinoma, … , an approach that is not consistent
with consensus guidelines and that complicates the generalization of these results to current

Thyroid cancer: a review

L Boucai, M Zafereo, ME Cabanillas - Jama, 2024 - jamanetwork.com
Anaplastic thyroid carcinoma is an undifferentiated and the most lethal form of thyroid cancer
Surgical resection is the preferred approach for patients with recurrent locoregional disease

Disruption of cell-cell communication in anaplastic thyroid cancer as an immunotherapeutic opportunity

S Chakraborty, M Carnazza, T Jarboe… - Tumor …, 2021 - Springer
… About 44,280 new cases of thyroid cancer (12,150 in men and 32,130 in women) are …
thyroid tumors are treatable and associated with a favorable outcome, anaplastic thyroid cancer (…

[HTML][HTML] Targeting transcriptional regulators for treatment of anaplastic thyroid cancer

WK Lee, SY Cheng - Journal of cancer metastasis and treatment, 2021 - ncbi.nlm.nih.gov
cancers [1,3–5] . In particular, the development of aggressive and therapeutically recalcitrant
tumors such as anaplastic thyroid cancer (… been no effective approach to directly controlling …

[HTML][HTML] Molecular diagnosis and targeted treatment of advanced follicular cell-derived thyroid cancer in the precision medicine era

J Capdevila, A Awada, D Führer-Sakel… - Cancer Treatment …, 2022 - Elsevier
… (PDTC; 0.3–6.7% of all cases); Hürthle cell cancers and anaplastic thyroid cancer (ATC; the
… a multimodal approach comprising surgery followed by high-dose external beam radiation …

[HTML][HTML] Thyroid Cancer: From Genes to Treatment–Recent Developments

I Kostoglou-Athanassiou - Thyroid Cancer-The Road From Genes …, 2023 - intechopen.com
… Although sorafenib was observed in combination with metformin to inhibit anaplastic thyroid
cancer cells [61], the drug was not effective in vivo in an anaplastic thyroid cancer patient [36]…

[HTML][HTML] Current perspectives on the management of patients with advanced RET-driven thyroid cancer in Europe

R Elisei, E Grande, MC Kreissl, S Leboulleux… - Frontiers in …, 2023 - frontiersin.org
Anaplastic thyroid cancer, also known as undifferentiated … This review provides a perspective
on the clinical benefit of such targeted therapies in advanced thyroid cancer to date, with a …

[HTML][HTML] Targeted therapy in advanced thyroid cancer

L Boucai - Frontiers in Endocrinology, 2022 - frontiersin.org
anaplastic thyroid cancer by targeting the specific molecular events that give rise to the tumor.
… underscores the progress made toward a personalized approach in the management of …