Efficacy of 3-day low dose quinine plus clindamycin versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan …

CO Obonyo, EA Juma, VO Were, BR Ogutu - Malaria Journal, 2022 - Springer
… courses have been associated with a lower treatment efficacy … In our study, the combination
of quinine with clindamycin was … low efficacy observed on the quinine plus clindamycin arm …

Quinine plus clindamycin vs artemether-lumefantrine for treatment of uncomplicated falciparum malaria in western Kenya

CO Obonyo, BR Ogutu - Malaria Journal, 2022 - Springer
… role of clindamycin-based combinations in the treatment of … outcome measures to assess
treatment efficacy. Our results … comparability of treatments (by using oral 12-hourly treatment for …

Efficacy of Quinine Plus Clindamycin Versus Artemether-Lumefantrine For The Treatment of Uncomplicated Plasmodium Falciparum Malaria In Kenyan Children …

C Obonyo, EA Juma, VO Were, BR Ogutu - 2021 - researchsquare.com
… In our study, the combination of quinine with clindamycin was well tolerated and had a
comparable … Children treated using quinine plus clindamycin were more likely to develop severe …

Clinical pharmacokinetics of quinine and its relationship with treatment outcomes in children, pregnant women, and elderly patients, with uncomplicated and …

T Saeheng, K Na-Bangchang - Malaria Journal, 2022 - Springer
… , and is always used in combination with an additional agent, such as doxycycline [1]. Quinine
is also used, in combination with clindamycin, for uncomplicated Plasmodium falciparum …

Critical Analysis of the Literature Comparing Artemisinin-Based Combination Therapy and Quinine Treatments for Uncomplicated Malaria in Pregnancy

DMP Nsonizau, DK Kouzitissa, N Wasadidi… - …, 2024 - research.manuscritpub.com
… This study shows that quinine monotherapy offers lower efficacy and tolerance than ACTs, …
than quinine-clindamycin. The need for studies comparing ACTs and quinine in dual therapy

Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines

KAJ Al Khaja, RP Sequeira - Malaria journal, 2021 - Springer
… variables that include therapeutic efficacy of drugs against P. … quinine monotherapy to treat
uncomplicated malaria during first trimester, instead of quinine plus clindamycin combination

In vitro effects of quinine on the antibacterial activity of erythromycin against bacteria of clinical relevance

OA Akinwale, UO Emokpae… - GSC Biological and …, 2021 - gsconlinepress.com
… not recommended when using clindamycin-containing products… seeing that synergy is a vital
part of therapeutic efficacy [58]. … on the effect of combining erythromycin with quinine against …

Antiplamodial effect of sulfadoxine/pyrimethamine/clindamycin: A study in parasitized mice

E Adıkwu, SI Ajeka, CO Nworgu - Bulletin of Biotechnology, 2022 - dergipark.org.tr
Clindamycin in combination with chloroquine or quinine is effective therapy for uncomplicated
Clindamycin plus quinine for treating uncomplicated falciparum malaria: a systematic …

An alternative combination therapy with metronidazole and doxycycline for babesiosis and theileriosis in stray dogs

KM Eldakhly - Egyptian Veterinary Medical Society of Parasitology …, 2021 - journals.ekb.eg
… In addition to monitor the therapeutic efficacy of clindamycin in combination with quinine
In addition, in this study the combination of clindamycin with quinine did not demonstrate the …

Treatment of human babesiosis: then and now

I Renard, C Ben Mamoun - Pathogens, 2021 - mdpi.com
… of human babesiosis is limited and consists of combinations of atovaquone and azithromycin
or clindamycin and quinine. These combination therapies were not designed based on …