Novel therapeutic targets for SARS-CoV-2-induced acute lung injury: Targeting a potential IL-1β/neutrophil extracellular traps feedback loop
A Yaqinuddin, J Kashir - Medical hypotheses, 2020 - Elsevier
… Strikingly, EIC − mutants produced low levels of proinflammatory cytokines including IL-6,
IL-… a potential mechanism of generating the exaggerated cytokine response in sepsis. …
IL-… a potential mechanism of generating the exaggerated cytokine response in sepsis. …
[HTML][HTML] Design of therapeutic biomaterials to control inflammation
… immunoglobulins, that are expressed on endothelial cells following activation by cytokines
50 . Therapeutic targeting of endothelial CAMs is a promising approach to managing vascular …
50 . Therapeutic targeting of endothelial CAMs is a promising approach to managing vascular …
Thymic stromal lymphopoietin: its role and potential as a therapeutic target in asthma
… in five approved biologic therapies for patients with … cytokine, provides an opportunity for
a novel approach to treat asthma inflammation. A member of a class of epithelial cytokines …
a novel approach to treat asthma inflammation. A member of a class of epithelial cytokines …
[HTML][HTML] Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position …
… Immunomodulatory therapies targeting cytokine storm show potential for such approaches
… the efficacy of immunomodulatory therapies in preventing cytokine storm induced severe …
… the efficacy of immunomodulatory therapies in preventing cytokine storm induced severe …
[HTML][HTML] Immune targets for therapeutic development in depression: towards precision medicine
… challenges for the elucidation of potential therapeutic targets 47 . Nevertheless, the … cytokines
or cytokine receptors, compounds that alter molecular factors that are induced by cytokines …
or cytokine receptors, compounds that alter molecular factors that are induced by cytokines …
[HTML][HTML] Cytokines and Janus kinase/signal transducer and activator of transcription signaling in prostate cancer: Overview and therapeutic opportunities
G Canesin, A Krzyzanowska, R Hellsten… - Current Opinion in …, 2020 - Elsevier
… mechanism mediating the action of cytokines, interferons, and growth factors for the control
of gene expression. Extracellular signals mediated by cytokines are thus transduced through …
of gene expression. Extracellular signals mediated by cytokines are thus transduced through …
The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics
M Abbasifard, H Khorramdelazad - Life sciences, 2020 - Elsevier
… receptors could be high potential diagnostic and therapeutic targets in COVID-19 patients [21].
… that Tocilizumab therapy may be valid only in COVID-19 patients with cytokine storms and …
… that Tocilizumab therapy may be valid only in COVID-19 patients with cytokine storms and …
[HTML][HTML] A Narrative Review of Cytokine Networks: Pathophysiological and Therapeutic Implications for Inflammatory Bowel Disease Pathogenesis
M Vebr, R Pomahačová, J Sýkora, J Schwarz - Biomedicines, 2023 - mdpi.com
… This cytokine–cell network has been shown to play essential … cytokine networks drive distinct
features and phase of IBD and provide a basis for potential alternative therapeutic targets of …
features and phase of IBD and provide a basis for potential alternative therapeutic targets of …
[HTML][HTML] Signaling pathways and targeted therapy for myocardial infarction
Q Zhang, L Wang, S Wang, H Cheng, L Xu… - … and targeted therapy, 2022 - nature.com
… , and exosome therapy have been emerging and are known as novel therapies. In this
review, we summarize the therapeutic strategies for MI by regulating these associated pathways, …
review, we summarize the therapeutic strategies for MI by regulating these associated pathways, …
[HTML][HTML] Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting
J Soppert, M Lehrke, N Marx, J Jankowski… - Advanced drug delivery …, 2020 - Elsevier
… effective and cost-efficient therapies to reduce cardiovascular risk are … Statins form the first-line
therapy with the aim to block … Also, an overview of applied as well as emerging therapeutic …
therapy with the aim to block … Also, an overview of applied as well as emerging therapeutic …