Clustering of major histocompatibility complex-class I molecules in healthy and cancer colon cells revealed from their nanomechanical properties

M Moretti, R La Rocca, M Perrone Donnorso, B Torre… - ACS …, 2021 - ACS Publications
Three-dimensional plotting and morphological data analysis were performed with the
free software Gwyddion. The histogram of the cell height data was obtained directly from the …

The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages

F Mompart, A Kamgoué, Y Lahbib-Mansais… - BMC Molecular and Cell …, 2021 - Springer
class I, III and II) in macrophages using 3D-FISH. Since this complex presents major differences
in humans … presence of the centromere between class III and class II regions in pigs, the …

[HTML][HTML] Extracellular crosslinking mass spectrometry reveals HLA class I–HLA class II interactions on the cell surface

G Armony, AJR Heck, W Wu - Molecular Immunology, 2021 - Elsevier
… the three-dimensional protein structures. As such, summarizing these restraints into possible
modes of interaction would be critical for structural modeling of these complexes. To this …

Structure and dynamics of major histocompatibility class Ib molecule H2-M3 complexed with mitochondrial-derived peptides

A Strand, ST Shen, DR Tomchick, J Wang… - … Structure and …, 2022 - Taylor & Francis
Three-dimensional structures of the four heptapeptide ND1-M3 complexes were determined
by X-ray crystallography. Protein expression, purification and crystallization methods, as …

Major histocompatibility complex antigens

PR Hess - Schalm's Veterinary Hematology, 2022 - Wiley Online Library
… Despite these interspecies genetic differences in the MHC, the three-dimensional structures
of MHC class I and class II molecules are well-conserved between species, reflecting a …

The zinc ions stabilize the three-dimensional structure and are required for the binding of staphylococcal enterotoxin-like protein P (SEIP) with MHC-II receptors

I Shulcheva, M Shchannikova, B Melnik… - Protein Expression and …, 2022 - Elsevier
histocompatibility complex class II (… structure of SElP. The functional activity of SElP
was investigated by the ability to interact with the histocompatibility antigen class II receptor (MHC-II) …

Peptide–MHC binding reveals conserved allosteric sites in MHC class I-and class II-restricted T cell receptors (TCRs)

Y He, P Agnihotri, S Rangarajan, Y Chen… - Journal of molecular …, 2020 - Elsevier
… The complete three-dimensional structure of the TCRαβ/CD3εγ/CD3εδ/CD3ζζ complex was
… fragments presented by major histocompatibility complex (MHC) molecules on antigen-…

pHLA3D: updating the database of predicted three-dimensional structures of HLA with HLA-DR, HLA-DQ and HLA-DP molecules

DMT e Oliveira, MSC Marroquim… - Human Immunology, 2021 - Elsevier
… of three-dimensional (3D) structures of HLA molecules, we … published 106 3D structures of
HLA class I molecules from the … more 127 3D structures of HLA class II molecules (41 DR, 42 …

[HTML][HTML] Predicting T cell receptor antigen specificity from structural features derived from homology models of receptor-peptide-major histocompatibility complexes

M Milighetti, J Shawe-Taylor, B Chain - Frontiers in Physiology, 2021 - frontiersin.org
… The pipeline takes a fasta file with a TCR, a peptide and a class I MHC, predicts its three
dimensional structure and extracts pairwise distances and binding energies for the interface (…

Structural comparison between MHC classes I and II; in evolution, a class-II-like molecule probably came first

Y Wu, N Zhang, K Hashimoto, C Xia… - Frontiers in …, 2021 - frontiersin.org
histocompatibility complex (MHC) molecules present peptide fragments of intracellularly
digested protein antigens to T cells (1, 2… similar type domains of pMHC-I and pMHC-II structures, …