Clustering of major histocompatibility complex-class I molecules in healthy and cancer colon cells revealed from their nanomechanical properties
… Three-dimensional plotting and morphological data analysis were performed with the
free software Gwyddion. The histogram of the cell height data was obtained directly from the …
free software Gwyddion. The histogram of the cell height data was obtained directly from the …
The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages
F Mompart, A Kamgoué, Y Lahbib-Mansais… - BMC Molecular and Cell …, 2021 - Springer
… class I, III and II) in macrophages using 3D-FISH. Since this complex presents major differences
in humans … presence of the centromere between class III and class II regions in pigs, the …
in humans … presence of the centromere between class III and class II regions in pigs, the …
[HTML][HTML] Extracellular crosslinking mass spectrometry reveals HLA class I–HLA class II interactions on the cell surface
… the three-dimensional protein structures. As such, summarizing these restraints into possible
modes of interaction would be critical for structural modeling of these complexes. To this …
modes of interaction would be critical for structural modeling of these complexes. To this …
Structure and dynamics of major histocompatibility class Ib molecule H2-M3 complexed with mitochondrial-derived peptides
A Strand, ST Shen, DR Tomchick, J Wang… - … Structure and …, 2022 - Taylor & Francis
… Three-dimensional structures of the four heptapeptide ND1-M3 complexes were determined
by X-ray crystallography. Protein expression, purification and crystallization methods, as …
by X-ray crystallography. Protein expression, purification and crystallization methods, as …
Major histocompatibility complex antigens
PR Hess - Schalm's Veterinary Hematology, 2022 - Wiley Online Library
… Despite these interspecies genetic differences in the MHC, the three-dimensional structures
of MHC class I and class II molecules are well-conserved between species, reflecting a …
of MHC class I and class II molecules are well-conserved between species, reflecting a …
The zinc ions stabilize the three-dimensional structure and are required for the binding of staphylococcal enterotoxin-like protein P (SEIP) with MHC-II receptors
I Shulcheva, M Shchannikova, B Melnik… - Protein Expression and …, 2022 - Elsevier
… histocompatibility complex class II (… structure of SElP. The functional activity of SElP
was investigated by the ability to interact with the histocompatibility antigen class II receptor (MHC-II) …
was investigated by the ability to interact with the histocompatibility antigen class II receptor (MHC-II) …
Peptide–MHC binding reveals conserved allosteric sites in MHC class I-and class II-restricted T cell receptors (TCRs)
Y He, P Agnihotri, S Rangarajan, Y Chen… - Journal of molecular …, 2020 - Elsevier
… The complete three-dimensional structure of the TCRαβ/CD3εγ/CD3εδ/CD3ζζ complex was
… fragments presented by major histocompatibility complex (MHC) molecules on antigen-…
… fragments presented by major histocompatibility complex (MHC) molecules on antigen-…
pHLA3D: updating the database of predicted three-dimensional structures of HLA with HLA-DR, HLA-DQ and HLA-DP molecules
DMT e Oliveira, MSC Marroquim… - Human Immunology, 2021 - Elsevier
… of three-dimensional (3D) structures of HLA molecules, we … published 106 3D structures of
HLA class I molecules from the … more 127 3D structures of HLA class II molecules (41 DR, 42 …
HLA class I molecules from the … more 127 3D structures of HLA class II molecules (41 DR, 42 …
[HTML][HTML] Predicting T cell receptor antigen specificity from structural features derived from homology models of receptor-peptide-major histocompatibility complexes
… The pipeline takes a fasta file with a TCR, a peptide and a class I MHC, predicts its three
dimensional structure and extracts pairwise distances and binding energies for the interface (…
dimensional structure and extracts pairwise distances and binding energies for the interface (…
Structural comparison between MHC classes I and II; in evolution, a class-II-like molecule probably came first
Y Wu, N Zhang, K Hashimoto, C Xia… - Frontiers in …, 2021 - frontiersin.org
… histocompatibility complex (MHC) molecules present peptide fragments of intracellularly
digested protein antigens to T cells (1, 2… similar type domains of pMHC-I and pMHC-II structures, …
digested protein antigens to T cells (1, 2… similar type domains of pMHC-I and pMHC-II structures, …