Fluids and vasopressors in septic shock: basic knowledge for a first approach in the emergency department

D Coen - Emergency Care Journal, 2023 - pagepressjournals.org
… Nevertheless, many aspects of treatment are still controversial, among these the approach
to the administration of fluids and vasopressors. Moreover, most clinical research on septic …

[图书][B] Septic shock and vasopressor therapy: The impact of excessive mean arterial pressure values

BC Mims - 2022 - search.proquest.com
higher MAP values clearly requires higher vasopressor doses. Problem. During vasopressor
… The duration of vasopressor exposure, mechanical ventilation, ICU stay, and hospital stay …

Modulation of oxidative and nitrosative stress attenuates microvascular hyperpermeability in ovine model of Pseudomonas aeruginosa sepsis

S Fukuda, Y Niimi, Y Hirasawa, ER Manyeza… - Scientific reports, 2021 - nature.com
… R-107 reduced microvascular hyperpermeability, rather we … with increased vascular
permeability. Second, we did not use the supportive therapies, such as antibiotics and vasopressors, …

Comparison of vasopressin versus norepinephrine in a pig model of refractory cardiogenic shock complicated by cardiac arrest and resuscitated with veno-arterial …

T Klein, D Grandmougin, Y Liu, S Orlowski, E Albuisson… - Shock, 2021 - journals.lww.com
… an increasing degree of pressure on the venous vascular … that vasopressor increased maximal
ECMO flow via increase … of vasopressin on vascular permeability since an improvement in …

The endothelial glycocalyx: a fundamental determinant of vascular permeability in sepsis

J Fernández-Sarmiento… - Pediatric Critical Care …, 2020 - journals.lww.com
… relationship to increased vascular permeability, especially in … different water resuscitation
strategies, vasopressors, etc. This … its importance in vascular permeability conservation and the …

Is the sympathetic system detrimental in the setting of septic shock, with antihypertensive agents as a counterintuitive approach? A clinical proposition

F Petitjeans, A Geloen, C Pichot, S Leroy… - Journal of Clinical …, 2021 - mdpi.com
… failure despite aggressive use of vasopressors and increasing lactic acidosis after 6 h of …
vasopressor requirement is linked to vascular hyporesponsiveness* [74]. Reciprocally, vascular

[HTML][HTML] Inodilators in septic shock: should these be used?

GA Ospina-Tascón… - Annals of Translational …, 2020 - ncbi.nlm.nih.gov
… , inotrope therapy should increase myocardial contractility and then stroke volume, while
counterbalancing increases in … , and increased permeability of vessels with capillary leakage …

[HTML][HTML] Should we initiate vasopressors earlier in patients with septic shock: A mini systemic review

HX Zhou, CF Yang, HY Wang, Y Teng… - World Journal of Critical …, 2023 - ncbi.nlm.nih.gov
… of vasopressors can diminish the capillary permeability by inhibiting inflammation. In one
experiment, norepinephrine prominently reduced the endothelial permeability resulting from …

Microcirculation-guided resuscitation in sepsis: the next frontier?

E Damiani, A Carsetti, E Casarotta, R Domizi… - Frontiers in …, 2023 - frontiersin.org
… (PBR), ie, the dimension of the permeable part of the glycocalyx allowing the penetration of
vasopressors. If MAP is too low and the microcirculation is altered, add a vasopressor. The …

Fluid therapy and the microcirculation in health and critical illness

ES Cooper, DC Silverstein - Frontiers in veterinary science, 2021 - frontiersin.org
… , bradykinin increases capillary permeability, thereby increasing … and increases capillary
permeability. Adrenomedullin … /exogenous vasopressors and/or increased venous pressure, ad (…