Establishing the therapeutic index of fluid resuscitation in the septic patient: a narrative review and meta‐analysis

PM Reynolds, L Wells, R MacLaren… - … : The Journal of …, 2020 - Wiley Online Library
… , thus increasing fluid distribution out of the vascular space. … Because capillary permeability
(and subsequent capillary … 42 reported an earlier time to the use of vasopressors in the …

A Guide to the Use of Vasopressors and Inotropes for Patients in Shock

AM Mergoum, AR Rhone, NJ Larson… - Journal of Intensive …, 2024 - journals.sagepub.com
… in an increased capillary permeability and dilation. Increased permeability allows fluid to …
Blood will pool in the capillary beds due to constriction of veins and dilation of arteries. The …

Microcirculation in patients with sepsis: from physiology to interventions

B Cantan, I Martín-Loeches - Annual Update in Intensive Care and …, 2020 - Springer
… did increase the risk of potentially lethal complications of fluid overload and increased capillary
permeability… between increases in arterial pressure produced by vasopressor agents and …

The Great Flood: An Exploration of Fluid Resuscitation in Sepsis

A Olsson - 2020 - idun.augsburg.edu
… system, increased permeability of the alveolar and capillary … received earlier vasopressors
had more vasopressor-free … Lastly, early vasopressor administration shortened the time it …

Comparison of predictive ability of macrocirculation and microcirculation markers on outcomes of patients with septic shock during initial fluid resuscitation: A …

K Shahsavarinia, T Sabzevari, K Shadvar… - Intensive Care …, 2024 - Springer
increased capillary permeability and fluid leakage into tissues [5, 6]. Additionally, elevated
… h were associated with an increased risk of using more than one vasopressor (OR: 6.506, 95…

Sepsis and Microcirculation

CEAO Jimenez - The Sepsis Codex, 2023 - Elsevier
… and that require vasopressors to maintain a mean arterial pressure (MAP) more than 65 mm
… Decreased vascular permeability causes vascular leakage and edema formation. RBC, red …

[HTML][HTML] Comparison of norepinephrine and terlipressin vs norepinephrine alone for management of septic shock: a randomized control study

P Sahoo, N Kothari, S Goyal, A Sharma… - Indian Journal of …, 2022 - ncbi.nlm.nih.gov
… caused a more significant reduction in total duration of vasopressor administration … vascular
permeability in septic shock. Liu et al., in the post hoc analysis of their trial, reported a higher

Effect of high-dose intravenous ascorbic acid on microcirculation and endothelial glycocalyx during sepsis and septic shock: a double-blind, randomized, placebo …

E Belousoviene, Z Pranskuniene, E Vaitkaitiene… - BMC …, 2023 - Springer
… , this dose of AA prevented an increase in capillary permeability [33]. … higher initial AA
levels (which could lead to a lower initial need for vasopressors) and receiving AA showed more

How I personalize fluid therapy in septic shock?

X Monnet, C Lai, JL Teboul - Critical Care, 2023 - Springer
… extravascular lung water and pulmonary vascular permeability index assess the risk of …
vasopressors, and a liberal strategy, prioritizing higher fluid volumes before starting vasopressors

The intensivist's perspective of shock, volume management, and hemodynamic monitoring

K Kashani, T Omer, AD Shaw - … Journal of the American Society of …, 2022 - journals.lww.com
… with more severe shock or in hospitals with a lower propensity to use vasopressors or fluids
… pressures) and the microcirculation (capillary permeability and perfusion, glycocalyx layer …