… ligament (ACL) is the most frequently injured ligament in the knee. The current method to treat
the injured ligament … Reconstruction requires the regeneration of ligament, bone and their …

… The transplantation of mesenchymal stem cells (MSCs) has been reported to improve
tendon, ligament and tendon-to-bone junction repair. MSC therapeutic area of the …

… Moreover, genetic diseases that affect connective tissue could have an impact on tendon/ligament.
Tendinopathies could be accompanied by inflammation and pain (as tendonitis, peri-…

… in tissue development and maintenance. Though tissue engineering approaches have yet
to fully recapitulate the biomechanical properties of native tendon and ligament, advances in …

… In this review, the nature of the tendon and the conventional … the different tendon tissue
engineering approaches that have … that allow adequate regeneration of the tendon: growth factors…

… Tissue engineering and regenerative medicine approaches aim to overcome these
disadvantages by stimulating the regeneration and … for tendon and ligaments tissue engineering is …

… The deficiencies of current approaches combined with the significant impact of these …
prompted the research of tissue engineering (TE) approaches for tendon/ligament regeneration [2, 7…

… in tissue repair and replacement. Biomaterials and tissue engineering approaches, … of
GAGs in bone, cartilage, tendon/ligament, and wound healing where the basic biology of …

… The ideal scaffold for tendon tissue engineering needs to exhibit … by promoting the
regeneration of the native tissue. … There are approximately 4000 tendons and ligaments in the …

… Traditionally, the principles of biomaterials and tissue engineering involve the use of a
suitable biocompatible scaffold onto which appropriate cell lines are cultured in the presence of …