… with the release of pro-inflammatory cytokines, interferons (… nM and whose binding pocket
partially overlaps that of the … to inhibit the production of pro-inflammatory cytokines upon LPS …

… agonists for the induction of macrophage tumoricidal activity and the production of both NO
and proinflammatory cytokines (… (APCs) secreted pro-inflammatory cytokines, including IFN-α, …

… that partial activation of TLRs is conducive to the production of anti-inflammatory factors and
nervous system repair. … , and promoting the production of pro-inflammatory cytokines. In the …

… These modulators are often small synthetic compounds and most act as agonists and to a …
which are classified firstly by their biological activities (agonist or antagonist) and then by their …

… It hinders TLR4 dimerization and it blocks pro-inflammatory cytokine production in monocytes
stimulated with synovial fluid from RA patients. NI-0101 has been tested in clinical trials in …

… distinct responses to LPS or partial structures. Unlike inbred … /Mal binding may in turn produce
pro-inflammatory cytokines. … However, TLR4 signalling is essential for injury repair. In brief…

… trigger an immunosuppressive effect, at least partially, via … by the expression of various
pro-inflammatory cytokines [54], … demonstrates that IDO-1 production and its enzymatic activity …

… partially by a more potent anti-CTLA-4 antibody and TLR9 … myeloid cells to produce
inflammatory cytokines such as TNF and … agonists result in secretion of proinflammatory cytokines, …

… with specific TLR agonists to restore the immune homeostasis. … An immune response to
dsRNA can be partially generated … to produce type I IFNs and proinflammatory cytokines. In the …

… mRNAs, along with nitrite production, were enhanced by p38 … Pro-inflammatory cytokines
are selectively regulated by MAPKs … , in comparison to TLR3 or TLR4 agonists. We found that …