[PDF][PDF] Adenosine A2A receptor signaling affects IL-21/IL-22 cytokines and GATA3/T-bet transcription factor expression in CD4 T cells from a BTBR T Itpr3tf/J mouse …

SF Ahmada, MA Ansaria, A Nadeema, SA Bakheeta… - Cytokines - academia.edu
… Our findings showed CTLA-4 signaling was greatly decreased in BTBR control and SCH-…
Toll-like receptors, NF-κB, and IL-27 mediate adenosine A2A receptor signaling in BTBR T+ …

… proinflammatory mediators and Notch-1 signaling in CD14+ and CD40+ cells and is associated with imbalance of neuroimmune function in BTBR T+ Itpr3tf/J mice

SF Ahmad, SA Bakheet, MA Ansari, A Nadeem… - Neurotoxicology, 2021 - Elsevier
… Our results showed that both the percentage of CD14 + NF-κB p65 + and CD40 + NF-κB
significantly decreased IL-27 production and expression in MeHgCl-exposed BTBR mice. This …

[HTML][HTML] Exploring the role of interleukin-27 as a regulator of neuronal survival in central nervous system diseases

AN Nortey, KN Garces, AS Hackam - Neural regeneration …, 2022 - journals.lww.com
… of Toll-like receptors, CD40, complement, and interferon (IFN) … Characterization of IL-27-mediated
signaling in neutrophils … The mechanism by which IL-27 inhibits NF-κB in these cells …

Nuclear factor kappa B in autism spectrum disorder: a systematic review

X Liao, Y Li - Pharmacological Research, 2020 - Elsevier
Toll-like receptor (TLR) signaling is … mediators signaling pathway in the BTBR mouse model
of ASD. The results showed a significant increase in the expression of NF-κB in BTBR mice, …

… exposure exacerbates immunological abnormalities in a BTBR T+ Itpr3tf/J autistic mouse model by upregulating inflammatory mediators in CD45R-expressing cells

TH Albekairi, MM Alanazi, MA Ansari, A Nadeem… - Journal of …, 2024 - Elsevier
NF-κB in BTBR mice. Furthermore, we discovered that giving Cd to BTBR mice increased
the expression of NF-κB p65 mRNA in brain tissue. The findings of this study suggest that …

Icariin alleviates autistic-like behavior, hippocampal inflammation and vGlut1 expression in adult BTBR mice

P Jiang, L Zhou, Z Du, L Zhao, Y Tang, X Fei… - Behavioural Brain …, 2023 - Elsevier
… the increased pro-inflammatory mediators caused by CMS(… And inhibition of toll-like
receptor(TLR4) and NF-κB signaling … neuronal toll-like receptors and COX-2 signaling in BTBR T(+…

Inhibition of tyrosine kinase signaling by tyrphostin AG126 downregulates the IL-21/IL-21R and JAK/STAT pathway in the BTBR mouse model of autism

SF Ahmad, MA Ansari, A Nadeem, SA Bakheet… - Neurotoxicology, 2020 - Elsevier
BTBR mice. We showed that the proportion of IL-27-producing CD8 + T cells decreased in
untreated BTBR … and anti-inflammatory effects, which are mediated by a reduction in pro-…

[HTML][HTML] Ibudilast attenuates folic acid–induced acute kidney injury by blocking pyroptosis through TLR4-mediated NF-κB and MAPK signaling pathways

X Li, Y Zou, YY Fu, J Xing, KY Wang, PZ Wan… - Frontiers in …, 2021 - frontiersin.org
Toll-like receptor 4 (TLR4), an important member of the … /NF-κB inflammatory signaling
pathway in FA-induced acute tubular injury. Immunofluorescence staining revealed that NF-κB

[HTML][HTML] Adenosine A2A Receptor in Bone Marrow-Derived Cells Mediated Macrophages M2 Polarization via PPARγ-P65 Pathway in Chronic Hypoperfusion Situation

KJ Mou, KF Shen, YL Li, ZF Wu… - Frontiers in Aging …, 2022 - frontiersin.org
… Next, we used lentivirus-mediated shRNA knockdown to further assess the role of PPARγ
in the macrophage polarization under low-glucose and hypoxic environment. The expression …

[HTML][HTML] Adenosine receptors in neuropsychiatric disorders: fine regulators of neurotransmission and potential therapeutic targets

S Pasquini, C Contri, S Merighi, S Gessi… - International Journal of …, 2022 - mdpi.com
adenosine on neurotransmission are mainly mediated by A 1 and A 2A adenosine receptors
… In the BTBR T+ Itpr3 tf /J (BTBR) mouse model of idiopathic autism, the acute administration …