[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation

JL Ables, K Park, I Ibañez–Tallon - Pharmacological research, 2023 - Elsevier
… the habenula's cholinergic and non-cholinergic components in … neurons also demonstrate
medial to lateral topographical … Nicotine and substance P differentially regulate neuronal …

Acetylcholine potentiates glutamate transmission from the habenula to the interpeduncular nucleus in losers of social conflict

M Kinoshita, H Okamoto - Current Biology, 2023 - cell.com
systems. Previously, we showed that the Hb-interpeduncular nucleus (IPN) pathway controls
… The zebrafish Hb-IPN pathway consists of three parallel pathways: lateral subnucleus of the …

Untangling the dorsal diencephalic conduction system: a review of structure and function of the stria medullaris, habenula and fasciculus retroflexus

…, B Lim, M Roman, D Barry, P Tierney… - Brain Structure and …, 2020 - Springer
… dorsal diencephalic conduction system (DDCS) is a highly conserved pathway linking the …
primarily cholinergic, glutamatergic and GABAergic, with primary GABAergic and cholinergic

Abundant extrasynaptic expression of α3β4-containing nicotinic acetylcholine receptors in the medial habenula–interpeduncular nucleus pathway in mice

A Tsuzuki, M Yamasaki, K Konno, T Miyazaki… - Scientific Reports, 2024 - nature.com
… co-release glutamate and substance P. Their inputs and outputs … pathway regulates the
activity of neuromodulatory systems … We next examined the vMHb with two cholinergic markers: …

[HTML][HTML] Feed-forward Activation of Habenula Cholinergic Neurons by Local Acetylcholine

L Chung, M Jing, Y Li, AR Tapper - Neuroscience, 2023 - Elsevier
… While the MHb consists of neurons with diverse gene expression, the nuclei contain a dense
cluster of cholinergic neurons on the ventral side and substance P neurons on the dorsal …

Functional α7 nicotinic acetylcholine receptors in GABAergic neurons of the interpeduncular nucleus

XT Jin, RM Drenan - Neuropharmacology, 2022 - Elsevier
… Dorsal medial habenula neurons are primarily peptidergic, releasing substance P (SP) … to
cholinergic modulation of neurotransmission in the habenulo-interpeduncular pathway. IPL α7 …

Cholinergic modulation of circuits

NA Addy, CD Fowler, RJ Wickham - Neurocircuitry of Addiction, 2023 - Elsevier
substance P and glutamatergic fibers from the dorsal MHb, whereas the central and intermediate
regions receive cholinergic … delineated and identified cholinergic pathways and circuits …

Unravelling the Role of Habenula Subnuclei on Avoidance Response: Focus on Activation and Neuroinflammation

GF Antunes, ACP Campos, DO Martins… - International Journal of …, 2023 - mdpi.com
… -opioid-receptor, but also P-type calcium channels, neurokinin-3 … These areas containing
substance P, cholinergic and … MHb-IPN glutamatergic-cholinergic pathway. The increase in FOS…

Distribution of nicotinic receptors in the CNS

EK Perry - CNS neurotransmitters and neuromodulators, 2020 - taylorfrancis.com
… peptides (eg, galanin in Chi, substance P in Ch5/6), and growth … both cholinergic and
noncholinergic input pathways together … receptors in the rat habenulo-interpeduncular system, J. …

Transcriptional and spatial resolution of cell types in the mammalian habenula

Y Hashikawa, K Hashikawa, MA Rossi, ML Basiri, Y Liu… - Neuron, 2020 - cell.com
The habenula complex is appreciated as a critical regulator of motivated and pathological
behavioral states via its output to midbrain nuclei. Despite this, transcriptional definition of cell …