[HTML][HTML] Towards reliable reconstruction of the mouse brain corticothalamic connectivity using diffusion MRI

TM Arefin, CH Lee, Z Liang, H Rallapalli, YZ Wadghiri… - Neuroimage, 2023 - Elsevier
Diffusion magnetic resonance imaging (dMRI) tractography has yielded intriguing insights
into brain circuits and their relationship to behavior in response to gene mutations or
neurological diseases across a number of species. Still, existing tractography approaches
suffer from limited sensitivity and specificity, leading to uncertain interpretation of the
reconstructed connections. Hence, in this study, we aimed to optimize the imaging and
computational pipeline to achieve the best possible spatial overlaps between the …

Towards reliable reconstruction of the mouse brain thalamocortical connectivity using diffusion MRI

TM Arefin, CH Lee, Z Liang, H Rallapalli, YZ Wadghiri… - bioRxiv, 2022 - biorxiv.org
Diffusion magnetic resonance imaging (dMRI) tractography has yielded intriguing insights
into brain circuits and their relationship to behavior in response to gene mutations or
neurological diseases across a number of species. Still, existing tractography approaches
suffer from limited sensitivity and specificity, leading to uncertain interpretation of the
reconstructed connections. Hence, in this study, we aimed to optimize the imaging and
computational pipeline for reliable reconstruction of the mouse brain thalamocortical …
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