[HTML][HTML] Identification of key genes by integrating DNA methylation and next-generation transcriptome sequencing for esophageal squamous cell carcinoma

Y Chen, LD Liao, ZY Wu, Q Yang, JC Guo… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… So we combined Signature-1 with pTNM stage to construct a new model with … and
transcriptomics to identify key genes underlying the tumorigenic processes of ESCC. Our study …

RNA-Seq for revealing the function of the transcriptome

K Goswami, N Sanan-Mishra - Bioinformatics, 2022 - Elsevier
… This can reveal critical information on the genes that are … about the various next-generation
sequencing platforms and … parallel signature sequencing (MPSS) is a unique signature-…

There is no hiding if you Seq: recent breakthroughs in Pseudomonas aeruginosa research revealed by genomic and transcriptomic next-generation sequencing

RXE Valli, M Lyng… - Journal of medical …, 2020 - microbiologyresearch.org
… increase in the number of whole-transcriptome experiments reported in the literature in both
… -transcriptome sequencing. Taking advantage of the independence of NGS from probes or …

[HTML][HTML] Next generation sequencing-based transcriptome data mining for virus identification and characterization: review on recent progress and prospect

M Rahimian, B Panahi - Journal of Clinical Virology Plus, 2024 - Elsevier
… the broad application of transcriptome data mining in virology… the versatility of transcriptomic
methods in revealing viral … of virus identification through transcriptome data. Each tool offers …

[HTML][HTML] Transcriptome and epigenome analysis of engram cells: next-generation sequencing technologies in memory research

M Fuentes-Ramos, M Alaiz-Noya, A Barco - Neuroscience & Biobehavioral …, 2021 - Elsevier
… been considerable progress in the transcriptomic and epigenomic analysis of experience-…
the transcriptome of both populations, describing a specific transcriptional signature for …

[HTML][HTML] Identification of novel gene signatures using next-generation sequencing data from COVID-19 infection models: focus on neuro-COVID and potential …

PN Pushparaj, AA Abdulkareem… - Frontiers in …, 2021 - frontiersin.org
… Additionally, single-cell transcriptomics data (GSE163005) of … bronchioalveolar immune
cells revealed important cellular and … In addition, single-cell transcriptomic data of immune cells …

Genome and transcriptome biomarkers of response to immune checkpoint inhibitors in advanced solid tumors

A Pender, E Titmuss, ED Pleasance, KY Fan… - Clinical Cancer …, 2021 - AACR
… Our results reveal that tumor mutation burden and immune expression signatures are efficient
at … Next-generation sequencing of germline DNA was uninformative; however, subsequent …

[HTML][HTML] Transcriptomics and solid tumors: The next frontier in precision cancer medicine

AM Tsimberidou, E Fountzilas, L Bleris… - Seminars in cancer …, 2022 - Elsevier
… Advances in next-generation sequencing (NGS) technologies … Early results of clinical trials
suggest that transcriptomic … with NGS, has revealed transcriptomic silencing of DNA mutations …

[HTML][HTML] Improved biomarker discovery through a plot twist in transcriptomic data analysis

N Sánchez-Baizán, L Ribas, F Piferrer - BMC biology, 2022 - Springer
… Here, we explore a plot twist to transcriptome data analysis: … + WGCNA to publicly available
transcriptomics data in one of the … of the transcriptome is essential to reveal the molecular …

Signature analysis of high-throughput transcriptomics screening data for mechanistic inference and chemical grouping

JA Harrill, LJ Everett, DE Haggard, LJ Word… - Toxicological …, 2024 - academic.oup.com
… 1 to allow for addition of transcriptomic reference samples following lysate preparation. After
… Close inspection of the heatmap revealed sets of signatures that are inversely modulated by …