[HTML][HTML] Transforming growth factor-β: a multifunctional regulator of cancer immunity

VW Xue, JYF Chung, CAG Córdoba, AHK Cheung… - Cancers, 2020 - mdpi.com
cancer progression. TGF-β actively shapes the TME via modulating the host immunity. …
how TGF-β signalling acts as a checkpoint regulator for cancer immunomodulation. A better …

[HTML][HTML] Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy

MKK Chan, ELY Chan, ZZ Ji, ASW Chan… - … of Targeted Anti …, 2023 - ncbi.nlm.nih.gov
… which suppress anti-tumor immunity in the cancer microenvironment. In a preclinical study,
anti-LAP treatment enhanced adaptive immune response against cancer reduced CD103 + …

[HTML][HTML] Extracellular vesicles and transforming growth factor β signaling in cancer

DM Rodrigues-Junior, C Tsirigoti, SK Lim… - Frontiers in cell and …, 2022 - frontiersin.org
cancer development. Thus, this review aims at summarizing the impact of EVs on TGF-β
signaling … , metastatic spread, immune evasion and response to anti-cancer treatment. Moreover…

[HTML][HTML] Transforming growth factor-β signaling in fibrotic diseases and cancer-associated fibroblasts

X Shi, CD Young, H Zhou, XJ Wang - Biomolecules, 2020 - mdpi.com
Transforming growth factor-β (TGF-β) signaling is essential in embryo development and …
Other cells like epithelial cells and immune cells also participate in the fibrosis via the …

[HTML][HTML] Targeting transforming growth factor-β signaling for enhanced cancer chemotherapy

J Chen, Z Ding, S Li, S Liu, C Xiao, Z Li, B Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
transforming growth factor-β (TGFβ) signaling have received tremendous attention for late-stage
cancer treatment since TGFβ signaling … the tumor immune microenvironment and cancer

Transforming growth factor β signaling pathway: A promising therapeutic target for cancer

Y Chen, C Di, X Zhang, J Wang, F Wang… - Journal of cellular …, 2020 - Wiley Online Library
Transforming growth factor β (TGF-β) is part of the transforming growth factor β superfamily
which is involved … The mechanisms of these two antibodies are relevant to immune reaction. …

[HTML][HTML] Transforming growth factor-β in tumour development

CB Trelford, L Dagnino… - Frontiers in Molecular …, 2022 - frontiersin.org
immune system destroy tumour cells as described in Figure 7. However, the addition of
transforming growth factor-β (… functions of the innate and adaptive immune systems. For instance, …

[HTML][HTML] Transforming growth factor-beta (TGF-β) signaling in cancer-A betrayal within

AB Baba, B Rah, GR Bhat, I Mushtaq… - Frontiers in …, 2022 - frontiersin.org
… through immune and stroma components. This oscillatory role of TGF-β to fight against
cancer or act as a traitor to collaborate and crosstalk with other tumorigenic signaling pathways …

TGF-β1–a truly transforming growth factor in fibrosis and immunity

M Lodyga, B Hinz - Seminars in cell & developmental biology, 2020 - Elsevier
… To no surprise, more than 1570 PubMed-indexed review articles have been published
between 2014 and 2019 with search key words ‘transforming growth factor β’ and ‘TGF’ and more …

[HTML][HTML] Transforming Growth Factor-β and Oxidative Stress in Cancer: A Crosstalk in Driving Tumor Transformation

V Ramundo, G Giribaldi, E Aldieri - Cancers, 2021 - mdpi.com
… of transforming growth factor β (TGF-β), a key cytokine central in tumorigenesis and cancer
immune system, allowing cancer cells to escape immune surveillance and increasing tumor …