[HTML][HTML] Emerging pharmacological therapies for ARDS: COVID-19 and beyond

S Horie, B McNicholas, E Rezoagli, T Pham… - Intensive care …, 2020 - Springer
… of lung injury and repair, and advances in supportive care, … ARDS therapies has been
further highlighted in the evolving COVID-19 pandemic, which causes severe acute respiratory

Acute lung injury

NT Mowery, WTH Terzian, AC Nelson - Current problems in surgery, 2020 - Elsevier
… use of a variety of pharmacologic interventions for the treatment of ALI (Table 1). Some of
the early ARDSNet trials are indicative of much of the pharmacologic research aimed at ALI. …

Personalized pharmacological therapy for ARDS: a light at the end of the tunnel

PL Silva, P Pelosi, PRM Rocco - Expert Opinion on Investigational …, 2020 - Taylor & Francis
… Personalized medicine targeting the different ARDS phenotypes has emerged as an option
… VILI and acute lung injury, as well as in patients with ARDS. Nevertheless, pharmacological

Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report

HS Kulkarni, JS Lee, JA Bastarache… - … journal of respiratory …, 2022 - atsjournals.org
… of lung injury have created the need to update the definition of experimental acute lung
injury (ALI). We queried 50 participants with expertise in ALI and acute respiratory distress …

[HTML][HTML] An update on current therapeutic drugs treating COVID-19

R Wu, L Wang, HCD Kuo, A Shannar, R Peter… - Current pharmacology …, 2020 - Springer
… in disease progression and is preceded by acute lung injury (ALI) [19]. This distinction may
inform treatmentEmerging data show that SARS-CoV-2 may lead to damage to other organs …

[HTML][HTML] MSC based therapies—new perspectives for the injured lung

J Behnke, S Kremer, T Shahzad, CM Chao… - Journal of clinical …, 2020 - mdpi.com
… entities bronchopulmonary dysplasia, asthma and the different forms of acute lung injury
and chronic pulmonary diseases in adulthood. While clinical trials are so far restricted to …

Thromboinflammation in COVID-19 acute lung injury

WB Mitchell - Paediatric respiratory reviews, 2020 - Elsevier
… number of patients requiring ventilatory support for respiratory failure and acute lung injury
(ALI). As more data is emerging it has become apparent that COVID-19 also presents with a …

Pathogenesis of pneumonia and acute lung injury

ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022 - portlandpress.com
acute lung injury and its most common cause, infectious pneumonia, can advance our approach
to precision targeted clinical interventions. … array of emerging therapies entering clinical …

Current status of cell-based therapies for respiratory virus infections: applicability to COVID-19

M Khoury, J Cuenca, FF Cruz… - European respiratory …, 2020 - Eur Respiratory Soc
… been demonstrated in other models of acute lung injuries [9]. The latter may be particularly
relevant for cytokine storm and it is likely that a combination of actions will be responsible. …

Systems pharmacology reveals the mechanism of activity of Ge-Gen-Qin-Lian decoction against LPS-induced acute lung injury: a novel strategy for exploring active …

Z Ding, R Zhong, Y Yang, T Xia, W Wang… - Pharmacological …, 2020 - Elsevier
… biology dealing with the representation of disease mechanisms of action (ie. with the
pharmacology of drug targets). As an emerging interdiscipline combining experimental assays and …