[HTML][HTML] Vascular Response of Triiodothyronine on Isolated Aortic Rings: Contribution of Redox Mechanisms

VC Pederiva, A Castro, A Belló-Klein… - Arquivos Brasileiros …, 2024 - SciELO Brasil
Triiodothyronine Potentiates Vasorelaxation via PKG/VASP … (PKG/VASP) pathway directly
on the vascular smooth muscle … or two layers of the vascular smooth muscle cell (VSMC), while …

Thyroid Hormone Signaling Mechanisms in the Heart and Vasculature

K Ojamaa, MA Carrillo-Sepulveda - Thyroid and Heart: A Comprehensive …, 2020 - Springer
using isolated resistance arterioles, or vascular smooth muscle and endothelial cells, or using
… showed that production of NO in vascular smooth muscle cells by T3 stimulation required …

Diastolic and Systolic Dysfunction of the Heart and Thyroid Hormone Abnormalities

YD Tang - Thyroid and Heart: A Comprehensive Translational …, 2020 - Springer
… , fibrosis, and aortic vasorelaxation responsiveness. There is … signaling effects, T3 also
potentiates vasodilatory effects via … rapid vascular relaxation via a PKG/VASP signaling pathway, …

[HTML][HTML] Vitamin D, thyroid hormones and cardiovascular risk: Exploring the components of this novel disease triangle

C Vassalle, A Parlanti, A Pingitore, S Berti… - Frontiers in …, 2021 - frontiersin.org
… , cellular growth and differentiation, and cardiac remodeling at cardiovascular level. VSMC
vascular smooth muscle cells, … thyroid stimulating hormone, T3 triiodothyronine, T4 thyroxine. …

Serum Free Triiodothyronine and the Responsiveness to Clopidogrel in Patients Undergoing Elective Percutaneous Coronary Intervention

Y Ye, X Zhao, Y Zeng - Advances in Therapy, 2021 - Springer
Thyroid hormone receptors are found in both the vascular endothelium and myocardium,
indicating that thyroid hormone signaling … function by increasing vasorelaxation and inducing …

[HTML][HTML] Nitration of protein kinase G-Iα modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: Implications for acute lung injury

EA Zemskov, X Wu, S Aggarwal… - Journal of Biological …, 2021 - ASBMB
Phosphodiesterase 3A (PDE3A) selectively cleaves the phosphodiester bond of cAMP and
is inhibited by cGMP, making it an important regulator of cAMP–cGMP signaling crosstalk in …

[HTML][HTML] Thyroid Hormone Resistance Syndrome: From Molecular Mechanisms to Its Potential Contribution to Hypertension

K Prakash, P Hamid - Cureus, 2023 - ncbi.nlm.nih.gov
… on vascular function, with both T3 and T4 acting as vasodilators on vascular smooth muscle
cells [… in reduced T3 levels and changes in the signaling of THs. DIO2 is crucial in regulating …

[HTML][HTML] Region-specific effects of antenatal/early postnatal hypothyroidism on endothelial NO-pathway activity in systemic circulation

DK Gaynullina, SI Sofronova, EK Selivanova… - Current Research in …, 2022 - Elsevier
… this occurs in other vascular regions. We hypothesized that developmental thyroid deficiency
is … alterations in the local thyroid hormones signaling in different vascular beds of previously …

Palmatine derivatives as potential antiplatelet aggregation agents via protein kinase G/vasodilator-stimulated phosphoprotein and phosphatidylinositol 3-kinase/Akt …

T Fan, Y Cheng, W Wei, Q Zeng, X Guo… - Journal of Medicinal …, 2022 - ACS Publications
… (10−14) Our recent study proves that BBR suppresses platelet activation through blocking
the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway, (15) which plays a crucial role …

[HTML][HTML] The association of thyroid hormones with coronary atherosclerotic severity in euthyroid patients

N Yu, L Wang, Y Zeng, Y Zhao, S Chen… - Hormone and …, 2022 - thieme-connect.com
The aim of the work was to explore the correlation between thyroid hormones and coronary
atherosclerotic severity. This cross-sectional study included 340 euthyroid patients who …