… as hypoxia, oxidative stress, and DNA damage, leading to the … ROS accumulation and lipid
peroxidation, such as elatol in T. … findings, these derivatives caused mitochondrial membrane …

… Similar to our findings, these derivatives caused mitochondrial membrane depolarization,
an … Trypanocidal action of (-)-elatol involves an oxidative stress triggered by mitochondria …

… The typical treatments for leishmaniasis involve pentavalent … resulting oxidative stress
is associated with mitochondrial … with sesquiterpene (−)-elatol caused membrane rigidity [34]. …

… by cells under conditions of oxidative stress, which has been … Mitochondria are a major
source of reactive oxygen species (… changes are related to cell damage caused by HNE, we …

… by trypanosomatids for modulating oxidative stress in place of … in mitochondria, which
produced intense disruption of the … Unlike silphiperfol-5-en-3-ol (IC 50 = 48.7 μg/mL), elatol and …

… active principle involved in the anti-Trypanosomal activity?”, 3) “… cruzi activity of saiyacenols
A, elatol, and ethanolic extracts … cause damage in the cell body and in the mitochondrion and …

… It is suggested that trypanocidal activity of the extract may be … Elatol, a sesquiterpene
isolated from a Brazilian strain of a … vacuolization and interference in mitochondrial function L. …

… 500 μM, which caused 25.8% hemolysis; for 6d, the effect on the … amazonensis, as well as
the effects of (−)-elatol on the … in response to oxidative stress since the mitochondria is affected …

… was caused by intense oxidative stress, probably involving … (-)-elatol has shown activity
against Trypanosoma cruzi in the … in the mitochondrial membrane potential, which in turn triggers …

… that oxidative stress plays role in the formation of thiram-induced tibial dyschondroplasia. …
Trypanocidal action of (-)-elatol involves an oxidative stress triggered by mitochondria …