… , lung cancer, and breast cancer brain metastases. We also … brain metastases and die
because of the limited efficacy of … in the brain metastases, suggesting a direct inhibitory effect of …

… have been developed that demonstrate efficacy in non-small-cell lung cancer (NSCLC) …
. Tyrosine kinase inhibitors show different anti-brain metastases efficacy in NSCLC: a direct …

… anti-tumoral efficacy of radiotherapy can be enhanced through the incorporation of epidermal
growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). These inhibitors possess the …

… trials have demonstrated that tyrosine kinase inhibitors (TKIs; eg… of anti–brain metastatic
tumor effect of multitargeted agents. … the potential efficacy of multitargeted inhibitor for BM in …

… lung cancer brain metastasis (LCBM), exhibited not only resistance to epidermal growth factor
receptor-tyrosine kinase inhibitor (… and AZD9291 showed comparable efficiency in treating …

… conclude that brigatinib shows a predicted efficacy similar to … Thus far, three generations
of ALK tyrosine kinase inhibitors (… ALK+ NSCLC patients [37–39], but no direct comparison …

… tyrosine kinase inhibitor (TKI), to the first-generation TKI erlotinib along with their daily vs
weekly dosing efficacy… of the homing of EGFR mutant lung cancer cells to the lungs of the mice …

… as well as other chemotherapy drugs all showed good anti-BM … by soaking and could
directly enter the brain without going … has shown better anti-brain metastasis activity than other …

… neck cancer, and non-small cell lung cancer 4 . However, HER-2-… As a tyrosine kinase
inhibitor that targets both epidermal … and lapatinib, the anti-brain metastases efficacy of Ang-MIC …

… Direct effects of radiation include a decrease in tight junction … Sorafenib, a tyrosine kinase
inhibitor, in the presence of … Enhanced anti-brain metastasis from non-small cell lung cancer of …