… Increasing evidence suggests that the intrinsic function of PD-L1 is crucial for the therapeutic
efficacy in cancer patients. Despite the advances in understanding PD-L1’s nonimmune-…

… The SP-sLips showed enhanced brain targeting and anti-brain cancer efficacy, as … (HER2),
a receptor tyrosine kinase that is upregulated in cells of several types of cancer, including an …

… , neurons, astrocytes, and other glial cells communicate via direct contact and cytokine-…
tested with respect to efficacy. To decouple the effects of various biochemical parameters and to …

… Lung cancer is the most frequently diagnosed … test the efficacy of cell-based anticancer
therapies, namely chimeric antigen receptor (CAR) T cells targeting the receptor tyrosine kinase-…

… ‐modulating drugs currently used in the treatment of MS include interferon beta (IFN‐β),
glatiramer acetate, natalizumab, and fingolimod and has given little evidence of effectiveness for …

… for CRC; however, the direct mechanisms underlying the anti-… efficacy of Fx-high wakame
in the mice [51]. Kong et al. … -activated protein kinase (MAPK), c-Jun NH 2 -terminal kinases …

… In case of lung cancer, cancer cells are supressed by … , JNK, ERK, as well as protein kinase
(MAPKs) activation by p38 mitogen. … , they have distinct ionization efficiency, which makes the …

… et al. showed that human ovarian and small-cell lung cancer … to the already commonly used
anti-brain tumor therapy, TMZ. … Capsaicin additionally demonstrates anticancer efficacy in …

… These compounds have shown promising effectiveness in … source of neuroprotective and
anti-brain-aging agents. … These processes can generate ROS that can directly damage DNA …

… cytokine secreted by microglia and macrophages, as an anti-brain tumor-initiating cell (BTIC)
therapy. Not only does TNF directly inhibit BTICs as a monotherapy, but in combination …