… of PM, for understanding resistance mechanisms, tumor cell … –15), suggesting that future
optimization of the procedure should … spread of chemotherapy throughout the peritoneal cavity. …

… with no peritoneal spread and … future avenue for efficient treatment of CRC patients with
limited risk of toxicity and adverse side effects. Thus, understanding the underlying mechanisms …

… The tendency of peritoneal recurrence in the MSS/EMT … role of EMT in the peritoneal
spread of cancer cells. In terms of … intraperitoneal TME are relevant to improved understanding …

… evolve future therapeutic strategies for peritoneal metastasis. … from colorectal cancer, for
which genetic understanding has … the identification of molecular mechanisms involved in long-…

… and biological understanding of these elements in PM of colorectal cancer needs more in …
histopathological and molecular characteristics between paired primary colorectal cancers, …

… However, to fully understand their success we must comprehend their manufacture, how
these … The peritoneum is a common site of dissemination in CRC, forming part of the natural …

… , a better understanding of the biology of peritoneal metastatic … in CRC-PM and could
direct future therapy development. … To identify putative determinants of peritoneal spread, we …

… To understand why PM respond poorly to current treatments, … peritoneal metastases
originating from colorectal cancer … already established peritoneal lesions can detach, spread, …

… key molecules involved with PM dissemination, with the potential to target these mechanisms
in the delivery of future … An understanding of both the anatomy and histophysiology of the …

… Understanding of the molecular process of PM and the potential … step in peritoneal
dissemination is the detachment of cancer cells … through future studies. Furthermore, it is …