Multiple functions of compatible solute ectoine and strategies for constructing overproducers for biobased production

W Zhang, K Liu, F Kong, T Ye, T Wang - Molecular Biotechnology, 2024 - Springer
… , primarily focusing on constructing metabolic pathways that afford highly efficient … more
details about their interactions. This information deepens our understanding of the underlying …

The ups and downs of ectoine: structural enzymology of a major microbial stress protectant and versatile nutrient

L Hermann, CN Mais, L Czech, SHJ Smits… - Biological …, 2020 - degruyter.com
ectoine biosynthesis and consumption, an understanding … avoid a metabolic bottleneck for
the supply of the ectoine … determinants required for the interactions of the monomers in the …

Microbial production of ectoine and hydroxyectoine as high-value chemicals

M Liu, H Liu, M Shi, M Jiang, L Li, Y Zheng - Microbial Cell Factories, 2021 - Springer
… from a clearer understanding of the ectoine hydroxylase, is … then increase the metabolic flux
from ASA to ectoine. Thus, the … flexibility by affecting the electrostatic interaction (D180V), the …

The compatible solute ectoine: protection mechanisms, strain developmnet, and industrial production

HJ Kunte, T Schwarz, EA Galinski - Biotechnological Applications of …, 2020 - degruyter.com
… to depict the molecular interaction of ectoine with biomolecules, … molecules do not disturb
the metabolism, even at high cytoplas… Microscopic understanding of preferential exclusion of …

Rational flux-tuning of Halomonas bluephagenesis for co-production of bioplastic PHB and ectoine

H Ma, Y Zhao, W Huang, L Zhang, F Wu, J Ye… - Nature …, 2020 - nature.com
… to improve the production yield of ectoine by employing various metabolic engineering …
ectoine and PHB production under balancing nitrogen supply in different growth phases 51,52 . …

Design & generation of an efficient E. coli cell-factory for the overproduction of the compatible solutes ectoine & hydroxyectoine

L Bethlehem - 2020 - bonndoc.ulb.uni-bonn.de
Understanding system-wide biology including the interplay of … Metabolic network, generated
in this study, showing ectoine … Circles represent carbon atoms, rectangles nitrogen atoms. …

Optimization of ectoine production from Nesterenkonia xinjiangensis and one-step ectoine purification

F Orhan, E Ceyran, A Akincioğlu - Bioresource Technology, 2023 - Elsevier
… determined that the interaction effect of these main factors (salt, carbon, nitrogen, and pH) …
pH and concentration of salt, carbon, and nitrogen for the highest ectoine production (1.07 g/L) …

Recent advances in production and applications of ectoine, a compatible solute of industrial relevance

P Kadam, M Khisti, V Ravishankar, V Barvkar… - Bioresource …, 2023 - Elsevier
Metabolic engineering of ectoine biosynthetic pathway has also been attempted to improve
its yield… We also understand that the major limitations in applying fermentation technology for …

Role of Carbon, Nitrogen, Phosphate and Sulfur Metabolism in Secondary Metabolism Precursor Supply in Streptomyces spp.

S Krysenko, W Wohlleben - Microorganisms, 2024 - search.ebscohost.com
… albaflavenone [86] and ectoines that are effective against … produced by Streptomyces can
allow for the interaction with … to better understand the morphology, physiology, metabolic

[HTML][HTML] Engineering Escherichia coli for high-yield production of ectoine

D Wang, J Chen, Y Wang, G Du, Z Kang - Green Chemical Engineering, 2023 - Elsevier
Metabolic engineering strategies employed for ectoineMetabolic engineering of the
typical industrial strains to produce ectoine under mild cultivation avoids the application of high …