… by 20 genes are grouped under osteogenesis imperfecta. Identification of causative genes
has strengthened the understanding of bone formation and mineralization. The mode of …

… Therefore, dual-energy x-ray absorptiometry (DXA) to evaluate bone mineral density may
aid in the diagnosis and management of children with more severe types of OI. …

… With no cure, researchers have investigated the use of cell therapy to correct the underlying
… This review summarizes the preclinical and clinical studies of MSCs in the treatment of OI. …

… of people with osteogenesis imperfecta (OI) experience hearing loss. There is no cure for
OI… Here, we conduct a systematic review and meta-analysis on the efficacy of treatments …

… Genes, in which mutations have been linked to osteogenesis imperfecta or related diseases,
are indicated. These genes are involved in signal transduction and gene expression (grey), …

… progress of health management of children with osteogenesis imperfecta from three … with
osteogenesis imperfecta and adolescents by multidisciplinary collaborative management can …

… Purpose of Review This review aims to provide a review of the multidisciplinary management
of infants with osteogenesis imperfecta (OI) during the first year of life, focusing on those …

… such as a software “upgrade”. Dose of treatment being given may be adjusted based on
either the absolute DXA-derived LSaBMD Z-score, or the trajectory of the Z-score. In general, …

… Osteogenesis imperfecta (OI) is a group of genetic disorders characterized by decreased
bone mass and increased bone fragility (brittle bone) due to a type I collagen abnormality. Its …

… osteogenesis imperfecta in pediatric populations, brittle bone disorder, treatment for
osteogenesis imperfecta, pain management… , long-term pain management, nursing intervention, …