… For example, upregulation of atrial specific K 2P 3.1 (TASK-1) currents in atrial fibrillation (AF)
patients was shown to contribute to atrial action potential duration shortening, a key …

… participate in the increased action potential duration and atrial … Indeed, miR-138-5p, which
is upregulated in the lungs of … A293 decreased RV fractional shortening, increasing the RV …

… , downregulation, or loss-of-function (LOF) mutation in K + … TASK-1 (TWIK-related acid sensitive
K + ) or K2P3.1, is a … action potential duration, suggesting that KCNK3 also contributes to …

… the cell will show a single action potential. The membrane … recent progress on understanding
the role of potassium … for a shorter duration of time when compared with the THIK-1 variant. …

… channels in modulating the atrial action potential and facilitating arrhythmogenic conditions…
downregulation, consequently diminishing muscarinic receptormediated atrial AP shortening …

… with AF to sinus rhythm samples we saw downregulation of KCNN2 in AF, as previously …
Inverse remodelling of K2P3. 1 K+ channel expression and action potential duration in left …

… upregulated in a human chronic AF cohort compared with … TASK1 channel upregulation
causes a shortened AP duration … , a lower current threshold for action potential initiation, and a …

… of the neurokinin-III receptor regulates action potential duration (APD) in isolated … 1 currents
are upregulated in patients suffering from AF, contributing to the pathological shortening …

… of cells with shorter action potential duration, however, its … and rabbit myocytes with chronic
CaMKIIδ C overexpression [… caused by downregulation of several potassium currents and …

… the action potential and … upregulation may contribute to pathological shortening of the atrial
APD as well. Pharmacologic blockade of this I TASK-1 currents could revert APD shortening …