[HTML][HTML] Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis

A Fava, J Buyon, L Magder, J Hodgin, A Rosenberg… - JCI insight, 2024 - ncbi.nlm.nih.gov
… , we studied the urine proteomic profiles of 225 patients with … the inability of proteinuria to
distinguish between LN classes, as … inactive lesions that follow crescentic glomerulonephritis, …

[HTML][HTML] Urinary biomarkers in lupus nephritis

CC Aragón, RA Tafúr, A Suárez-Avellaneda… - Journal of translational …, 2020 - Elsevier
… with patients with inactive LN or quiescent lupus [159]. … urine of pediatric patients with active
LN, using proteomics … there is a greater differentiation toward the Th1 profile because of the …

Proximity extension assay proteomics and renal single cell transcriptomics uncover novel urinary biomarkers for active lupus nephritis

Y Li, C Tang, K Vanarsa, N Thai, J Castillo… - Journal of …, 2024 - Elsevier
… We first examined the gene expression profiles of the implicated biomarkers in a scRNA …
their accuracy and reliability in distinguishing active LN from inactive SLE. Their performances …

Urinary peptides as potential non-invasive biomarkers for Lupus Nephritis: results of the Peptidu-LUP Study

…, Groupe Coopératif sur le Lupus Rénal (GCLR) - Journal of Clinical …, 2021 - mdpi.com
… phases of LN and that urine proteome/peptidome analysis could … urinary peptidomics did
not differentiate between active LN … between samples with active LN and samples with inactive

Urinary biomarkers for lupus nephritis: a systems biology approach

MH Omer, A Shafqat, O Ahmad, J Nadri… - Journal of Clinical …, 2024 - mdpi.com
Urinary miRNA-21 could distinguish between inactive and … The application of urinary proteomic
techniques to identify biomarker … Comparing NMR-based metabolomic profiling in seven …

Exploring urine: serum fractional excretion ratios as potential biomarkers for lupus nephritis

SA Soliman, S Stanley, K Vanarsa, F Ismail… - Frontiers in …, 2022 - frontiersin.org
… Within each set of plots, the urine profiles are plotted to the … difference between active
renal, inactive SLE and controls. … active lupus nephritis from inactive SLE (top) and active

POS0297 PROTEOMIC ANALYSIS OF HISTOLOGICAL LESIONS LUPUS NEPHRITIS IDENTIFIES AN INFLAMMATORY SIGNATURE OF FIBROUS CRESCENTS

AI Celia, J Hodgin, D Demeke, A Rosenberg, L Magder… - 2023 - ard.bmj.com
… Pre-treatment gene expression profiles were compared in those who … Background: We
employed urine proteomics to define the … inactive lesions that follow crescentic glomerulonephritis, …

Comprehensive urinomic identification of protein alternatives to creatinine normalization for diagnostic assessment of lupus nephritis

S Soomro, S Stanley, R Lei, R Saxena, M Petri… - Frontiers in …, 2022 - frontiersin.org
distinguishing active lupus nephritis from inactive SLE patients. … Specifically, a comprehensive
proteomic screen of 1129 … (lupus nephritis) and healthy urine samples to identify urinary

P34 Urinary proteomics in lupus nephritis–prospective study in a tertiary care center

R Ramamoorthy, K Manoharan, B Kumar - 2020 - lupus.bmj.com
… of urinary biomarkers MCP1 and NGAL with the disease activity in lupus nephritis (LN). …
divided into 3 groups, 1st group with Active Lupus Nephritis (n=22), 2nd group with Inactive

Novel biomarkers for lupus nephritis in the “OMICS” era

R Dias, UG Hasparyk, MP Lopes… - Current medicinal …, 2021 - ingentaconnect.com
Proteomics consists of several methods that can identify and … the urine of patients with active
LN, differentiating active renal … uNGAL is able to distinguish active from inactive LN [228] […