Serum proteome and metabolome uncover novel biomarkers for the assessment of disease activity and diagnosing of systemic lupus erythematosus

J He, D Tang, D Liu, X Hong, C Ma, F Zheng, Z Zeng… - Clinical …, 2023 - Elsevier
… be used to discriminate active and inactive SLE patients, we … with SCr and 24 h urine
protein quantity, and negatively … alterations in the proteome and metabolome profiles in SLE …

Systemic lupus erythematosus, lupus nephritis and end-stage renal disease: a pragmatic review mapping disease severity and progression

A Mahajan, J Amelio, K Gairy, G Kaur, RA Levy… - Lupus, 2020 - journals.sagepub.com
… investigation, including additional autoantibodies and urinary proteomics, which might help
detect … Another study demonstrated a significant difference between the proportion of black …

Potential urine proteomic biomarkers for focal segmental glomerulosclerosis and minimal change disease

NV Chebotareva, A Vinogradov… - International Journal of …, 2022 - mdpi.com
… Our aim was to determine of the proteomic profile of urine … in MCD and in the urine in lupus
nephritis, and it appears to … , but no significant differences between these two forms were …

Inflammatory markers in saliva and urine reflect disease activity in patients with systemic lupus erythematosus

G Ruacho, R Lira-Junior, I Gunnarsson… - Lupus Science & …, 2022 - lupus.bmj.com
… -1 has been described to predict lupus nephritis (LN).6 9 The … Interestingly, proteomic analysis
of saliva from patients with … and active from inactive SLE, suggesting that both saliva and …

Study of the relationship between urinary level of uromodulin, renal involvement and disease activity in patients with systemic lupus erythrematosus

RN Bedair, MMA Ismail, EW Gaber… - Saudi Journal of …, 2020 - journals.lww.com
Lupus nephritis (LN) is a common and serious complication … between urinary uromodulin
levels in active and inactive LN … for the use of urinary proteomic profiling of renal injury and/or …

New biomarkers in SLE: from bench to bedside

R Capecchi, I Puxeddu, F Pratesi, P Migliorini - Rheumatology, 2020 - academic.oup.com
… variable in discriminating active from inactive patients. Before … exclusively in active lupus
nephritis; moreover, urinary CD4 T … urine proteomics and renal single-cell genomics identify an …

IGFBP2 function as a novel biomarker for active lupus nephritis

H Li, J Liang, Y Gao, M Liu, N Xia, W Kong… - Journal of Molecular …, 2022 - Springer
… The proteomic profiling of nine patients with active LN using TMT-LC–MS/MS was analyzed
on … significant difference between urinary IGFBP2 in patients with inactive (n = 19) and active

Prediction of prognosis and renal outcome in lupus nephritis

I Parodis, F Tamirou, FA Houssiau - Lupus science & medicine, 2020 - lupus.bmj.com
… the urinary sediment differ substantially between proliferative … inactive non-renal SLE to
active non-renal and active renal SLE. … proteomic screening of serum markers in systemic lupus

[图书][B] The Exploration of Non-Invasive Biomarkers for Lupus Nephritis

A Akhgar - 2021 - search.proquest.com
… multiplex analysis of urine proteomics to develop algorithms … renalase concentrations in
active vs inactive lupus nephritis ....… They found a significant difference between the groups with …

Diagnostic test accuracy of novel biomarkers for lupus nephritis—An overview of systematic reviews

JAR Guimarães, SC Furtado, ACS Lucas, B Mori… - PLoS …, 2022 - journals.plos.org
… serum and urinary biomarkers for diagnosing lupus nephritis in … and chronic renal lesions
and the differentiation between LN … inactive SLE, and patients with active SLE without nephritis. …