… animal models and recent clinical trials have significantly advanced our understanding of
bone cancer pain … Osteoclasts play an essential role in cancer-induced bone destruction and …

… cells are reportedly related to breast cancer-induced bone pain. Their secretion could be …
pain and reduced bone loss and fracture in the breast cancer-induced bone pain mouse model […

… aspects of pain and understand the cellular and … of animal models, from simple organisms
to rodents and non-human primates and the specific traits of pain pathologies they model. We …

… (43) Although further studies are necessary to understand the … actual role of the chemokines
in bone-cancer-induced pain. … hyperalgesia in various animal models of BCP. Several other …

… Due to a limited understanding of the pathophysiology driving … , immunocompetent mouse
model of bone metastasis and CIBP. The B6 Hi-Myc transgenic mouse model of prostate …

… analgesic effects in animal models of bone cancer pain. Here, we … alleviate pain sensation
in a mouse model of bone cancer pain. … Understanding the underlying molecular and cellular …

… , our current understanding of SN innervation of bone is briefly overviewed. … bone diseases
causing devastating bone pain [80]. We demonstrated [29], using a xenograft mouse model, …

… reduced opioid antinociception in cancer-induced bone pain. These results demonstrate …
of cancer-related pain by opioids in mouse models; these findings may impact the use of Hsp90 …

… to understand how tumor-induced primary and distal pain sensitivities are affected by
bupivacaine-induced block of bone nerve endings in a rat model of … in the animal model, ambient …

… used have been criticized. This study aimed to identify in detail pain phenotypes of cancer-induced
bone pain (… In this study, we use an established animal model in rats to identify a sex-…