Pharmacotherapeutic interventions in Parkinson's disease: investigating prescribing factors and health outcomes

K Orayj - 2020 - orca.cardiff.ac.uk
… of prescribing of Parkinson’s medications in newly diagnosed People with Parkinson's disease
(… After conducting a thorough systematic literature review, a retrospective study of PwP in …

Novel and experimental therapeutics for the management of motor and non-motor Parkinsonian symptoms

I Ullah, X Wang, H Li - Neurological Sciences, 2024 - Springer
… , a multicenter retrospective study involving 82 PD patients … NMDA receptors have a unique
ability to treat levodopa-induced-… The dibenzodiazepine clozapine has substantial activity …

[HTML][HTML] Precision medicine in parkinson's disease: From genetic risk signals to personalized therapy

G Straccia, F Colucci, R Eleopra, R Cilia - Brain Sciences, 2022 - mdpi.com
… for a recent retrospective study comparing baseline UPDRS III … the symptomatic treatment of
levodopa-induced dyskinesias … first-line treatment options include quetiapine and clozapine. …

[HTML][HTML] Overview of movement disorders secondary to drugs

JP Rissardo, N Vora, B Mathew, V Kashyap… - Clinics and …, 2023 - mdpi.com
clozapine. It has also been shown that anticholinergics such as benztropine and trihexyphenidyl
can be used to treat … in people with Parkinson’s disease is levodopa-induced dyskinesia…

Degenerative movement disorders of the central nervous system

AA Qutubuddin, P Chandan, W Carne - Braddom's Physical Medicine and …, 2021 - Elsevier
… There has been some evidence that treatment with clozapine … and a lower risk of
levodopa-induced motor complications. Box … A retrospective analysis of pathologically confirmed …

Cognitive dysfunction and neuropsychiatric aspects of Parkinson's disease

G Austgen, L Marsh - Progress in Brain Research, 2022 - Elsevier
… -treated, and the role of the underlying neurological disease is often … of PD, this chapter
reviews how cognitive changes in PD … , phenomenology, pathophysiology, and treatment of each. …

[HTML][HTML] Recent advances in the pharmacology of tardive dyskinesia

SN Caroff - Clinical Psychopharmacology and Neuroscience, 2020 - ncbi.nlm.nih.gov
… in levodopa-induced dyskinesias in Parkinson’s disease … or better response of TD in one
retrospective study [125]. Interestingly, … Clozapine monotherapy as a treatment for antipsychotic-…

[HTML][HTML] Treatment of dystonia: medications, neurotoxins, neuromodulation, and rehabilitation

IO Bledsoe, AC Viser, M San Luciano - Neurotherapeutics, 2020 - Elsevier
… to levodopa without levodopa-induced dyskinesia is described … Clozapine requires frequent
blood draws to monitor for … A retrospective study in 1988 involving 108 patients showed 20% …

Regulatory Implications of Inadequately Designed Pimavanserin Drug Trials Published with Risk of Bias on Expedited Regulatory Approval Processes

B Law - 2023 - search.proquest.com
… As such, this project will be a retrospective study with the research question “was there
enough quality evidence and suitably designed trials to warrant an accurate safety and efficacy …

Treatment of tardive dyskinesia

HH Bashir, J Jankovic - Neurologic Clinics, 2020 - neurologic.theclinics.com
… If patients require continued treatment, then every effort should be made to switch to medication
with lower risk of TD. In the cases of antipsychotics, switching to clozapine or quetiapine …