A Retrospective Case Series on Valproic Acid for Early Post-Traumatic Seizure Prophylaxis After Traumatic Brain Injury in Patients With Concomitant Agitation
D Nicole Gilliam, P Sarangarm… - Hospital …, 2023 - journals.sagepub.com
… prophylaxis and agitation is limited. The purpose of this study is to examine the safety
and efficacy of valproic acid for both early post-traumatic seizure prophylaxis and agitation. …
and efficacy of valproic acid for both early post-traumatic seizure prophylaxis and agitation. …
[HTML][HTML] Effectiveness of antiseizure medications therapy in preventing seizures in brain injury patients: A network meta-analysis
X Huo, X Xu, M Li, L Xiao, Y Wang, W Li… - Frontiers in …, 2022 - frontiersin.org
… The interventions involved the use of ASMs such as phenytoin, valproate, PB, LAM, LEV, …
The total NOS score of the included 18 non-randomized trials was above 5, indicating high …
The total NOS score of the included 18 non-randomized trials was above 5, indicating high …
[HTML][HTML] … efficacy of prophylactic anticonvulsant drugs following traumatic brain injury: A systematic review and network meta-analysis of randomized controlled trials
BC Wang, HY Chiu, HT Luh, CJ Lin, SH Hsieh… - PloS one, 2022 - journals.plos.org
… study by using version 2 of the Cochrane tool for assessing risk of bias in randomized trials
(… phenytoin and other AEDs, including levetiracetam and valproate, were compared [9]. The …
(… phenytoin and other AEDs, including levetiracetam and valproate, were compared [9]. The …
[HTML][HTML] Effect of levetiracetam and valproate on late-onset post-traumatic seizures
Y Wang, Y Wang, H Wang, X Du, J Miao, JX Tao… - Acta Epileptologica, 2023 - Springer
… of late post-traumatic seizures in the LEV group was significantly lower than those in the
valproate … The cumulative incidence of late post-traumatic seizure in the valproate group was not …
valproate … The cumulative incidence of late post-traumatic seizure in the valproate group was not …
[HTML][HTML] Multicenter and prospective trial of anti-epileptics for early seizure prevention in mild traumatic brain injury with a positive computed tomography scan
M Pease, M Zaher, AJ Lopez, S Yu… - Surgical Neurology …, 2022 - ncbi.nlm.nih.gov
… Posttraumatic seizures (PTSs) are a major source of disability after … seizures before
arrival at the hospital were prescribed AEDs for therapeutic intent and excluded from this study…
arrival at the hospital were prescribed AEDs for therapeutic intent and excluded from this study…
[HTML][HTML] Discontinuation of Levetiracetam and Valproic Acid Due to Adverse Effects in Early Post-traumatic Seizure Prophylaxis
SM Pathak, R Ziechmann, J Menzer, A Hoeft… - Cureus, 2023 - ncbi.nlm.nih.gov
… Introduction: Levetiracetam (LEV) and valproic acid (VPA) are two anti-epileptic drugs (AEDs)
routinely used for post-traumatic seizure (PTS) prophylaxis at our institution. In our practice…
routinely used for post-traumatic seizure (PTS) prophylaxis at our institution. In our practice…
[HTML][HTML] Preventing epilepsy after traumatic brain injury: a propensity score analysis
JH Liou, YL Chang, HT Lee, MF Wu… - Journal of the …, 2020 - journals.lww.com
… In a randomized study, TBI patients were administered phenytoin (… on late PTE, treatment
with PHE decreased the early seizure rate … , valproic acid, and levetiracetam with the non-AED …
with PHE decreased the early seizure rate … , valproic acid, and levetiracetam with the non-AED …
Comparison of the efficacy and safety of sodium valproate versus levetiracetam in the treatment of severe traumatic brain injury
X Huang, W Lin, J Wang, C Liu, G Wei… - International Journal …, 2024 - Taylor & Francis
… stress, thereby indirectly contributing to the prevention of seizures and post-traumatic epilepsy.
By integrating these preventive measures into the treatment regimen, our goal was to not …
By integrating these preventive measures into the treatment regimen, our goal was to not …
Use of Anti-epileptic Drugs for Post Traumatic Seizure: A Global Survey
H Gopalan, KP - Annals of neurosciences, 2023 - journals.sagepub.com
… In our survey 91.8% of people were giving AED for seizure prophylaxis in TBI, while …
treatment although prophylactic use of phenytoin or valproate is not recommended for preventing …
treatment although prophylactic use of phenytoin or valproate is not recommended for preventing …
Early seizure prophylaxis in mild and moderate traumatic brain injury: a systematic review and meta-analysis
… absolute risk reduction of seizure prophylaxis for early posttraumatic seizures was 0.6% in
… Valproate therapy for prevention of posttraumatic seizures: a randomized trial. J Neurosurg. …
… Valproate therapy for prevention of posttraumatic seizures: a randomized trial. J Neurosurg. …