… and immune evasion. Overcoming the challenge posed by … to be associated with different
invasion pathways. To this end, we … changes that mediate phenotypic variation will be the focus …

… to enzymatic treatment, two main invasion pathways for P. … erythrocytes against complement
or phagocytosis-mediated … invasion receptors change over the lifespan of the RBC? …

… variation associated with the use of alternative RBC invasion … relevance to RBC surface
remodeling and immune evasion in … bind RBC receptors but mediate later steps of invasion and …

… We identified 50 spots with ≥1.3-fold change in intensity in 1 or … EBA-175 to mediate invasion
in certain strain backgrounds … of CD44related pathways as targets for malaria intervention. …

… This phenomenon is termed ‘antigenic variation’ and it allows P. falciparum to evade the
host immune … Figure 2 The signaling pathways mediated by inhibitory immune receptors. The …

… Invasion of erythrocytes by Plasmodium merozoites is a complex multi-step process that
is mediated … and parasite ligands [8] which varies according to genetic background of the …

… some Plasmodium falciparum and Plasmodium vivax … of the main immune response
evasion mechanisms), several … vivax have multiple, complex RBC invasion routes mediated by …

… Variation in invasion pathway usage has been observed in the often lethal Plasmodium
falciparum … of immune evasion and cellular age tropism, as well as P. vivax pathogenesis. …

… falciparum could exploit the host cellular pathways to modulate the immune response. …
a greater capacity for antigenic variation and evasion of variant-specific immune responses (114). …

… , and while this flexibility is thought to facilitate immune evasion, … that variation in parasite
proliferation in vivo among P. … strategies–mediated by the use of different invasion pathways–in …