Mechanisms ensuring endothelial junction integrity beyond VE-cadherin
CN Duong, D Vestweber - Frontiers in Physiology, 2020 - frontiersin.org
… This also highlights a central difference between endothelial junctions in vitro and in vivo. In
… Furthermore, it was found recently that local microvascular leakage promotes movement of …
… Furthermore, it was found recently that local microvascular leakage promotes movement of …
VE-cadherin endocytosis controls vascular integrity and patterning during development
CM Grimsley-Myers, RH Isaacson, CM Cadwell… - Journal of Cell …, 2020 - rupress.org
… defects in VE-cad DEE/DEE mutants, we performed ex vivo aortic … cadherin-independent
roles for p120 in vascular endothelial … expression levels are the critical determinant controlling …
roles for p120 in vascular endothelial … expression levels are the critical determinant controlling …
Interference with ESAM (endothelial cell-selective adhesion molecule) plus vascular endothelial-cadherin causes immediate lethality and lung-specific blood …
CN Duong, AF Nottebaum, S Butz… - … , and Vascular …, 2020 - Am Heart Assoc
… We conclude that ESAM is essential for vascular integrity in … ) with mouse lung microvascular
endothelial cells (MLMVEC) … vivo results (Figure 1C), the mAb BV13 against VE-cadherin …
endothelial cells (MLMVEC) … vivo results (Figure 1C), the mAb BV13 against VE-cadherin …
[HTML][HTML] Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
… Vascular endothelial (VE)-cadherin in endothelial adherens junctions is an essential component
of the vascular … was seen in vitro; exposure of human umbilical vein endothelial cells (…
of the vascular … was seen in vitro; exposure of human umbilical vein endothelial cells (…
Blood endothelium transition and phenotypic plasticity: A key regulator of integrity/permeability in response to ischemia
N Bréchot, A Rutault, I Marangon, S Germain - Seminars in Cell & …, 2023 - Elsevier
… -cadherin antibody was responsible for a major vascular … surface of vascular endothelial
cells and plays a pivotal role for … vivo, microvascular human ECs (HMEC) and human umbilical …
cells and plays a pivotal role for … vivo, microvascular human ECs (HMEC) and human umbilical …
PI3KC2β inactivation stabilizes VE‐cadherin junctions and preserves vascular integrity
T Anquetil, R Solinhac, A Jaffre, G Chicanne… - EMBO …, 2021 - embopress.org
… vascular endothelial (VE)‐cadherin‐mediated homotypic cell–cell adhesion, is a key determinant
of vascular … To gain insight into the role of PI3KC2β in endothelium integrity in vivo, we …
of vascular … To gain insight into the role of PI3KC2β in endothelium integrity in vivo, we …
Integrin-Dependent Cell–Matrix Adhesion in Endothelial Health and Disease
J Aman, C Margadant - Circulation Research, 2023 - Am Heart Assoc
… interactions of vascular endothelial-cadherin (VE-cadherin), … and human pulmonary
microvascular ECs in vitro, as well as … Hemodynamic shear stress is an important determinant of …
microvascular ECs in vitro, as well as … Hemodynamic shear stress is an important determinant of …
Soluble vascular endothelial-cadherin in CSF after subarachnoid hemorrhage
… , we performed in vitro studies to determine the effect of sVE-cadherin on microglia, the major
… that during brain inflammation, sVE-cadherin is released from injured brain microvascular …
… that during brain inflammation, sVE-cadherin is released from injured brain microvascular …
Fibrinogen Fragment X Mediates Endothelial Barrier Disruption via Suppression of VE-Cadherin
SA Olson, BK Osborn, ME Cotton, JD Krocker… - Journal of Surgical …, 2024 - Elsevier
… vascular endothelium is a key determinant of normal organ function through its tightly controlled
regulation of coagulation, inflammation, and barrier integrity… restricted to in vitro, static …
regulation of coagulation, inflammation, and barrier integrity… restricted to in vitro, static …
Permeability of the endothelial barrier: identifying and reconciling controversies
… Here, we describe recent in vivo findings and other … Endothelial junction integrity is regulated
by proteins that form … not reflect regions of the microvasculature that leak in vivo; and (iv…
by proteins that form … not reflect regions of the microvasculature that leak in vivo; and (iv…