Lung-protective ventilation attenuates mechanical injury while hypercapnia attenuates biological injury in a rat model of ventilator-associated lung injury

N Ismaiel, S Whynot, L Geldenhuys, Z Xu… - Frontiers in …, 2022 - frontiersin.org
… : Lung-protective mechanical ventilation is known to attenuate ventilator-associated lung
injury (… , it is possible that the short duration of ventilation (a total of 4 h, 1 h to establish acute

Monitoring lung injury severity and ventilation intensity during mechanical ventilation

E Rezoagli, JG Laffey, G Bellani - … Respiratory and Critical Care …, 2022 - thieme-connect.com
lung injury severity and facilitate optimization of mechanical ventilation. Indices of lung injury
… , ventilatory setting and respiratory mechanics, ventilation intensity, and the presence of …

Prevention and treatment of acute lung injury with time-controlled adaptive ventilation: physiologically informed modification of airway pressure release ventilation

GF Nieman, LA Gatto, P Andrews, J Satalin… - Annals of intensive …, 2020 - Springer
… according to the mechanical characteristics of the lung. The … and protects lungs with, or at
high risk of, acute lung injury. We … duration of the release phase changes with changing lung

Characteristics and outcomes in patients with ventilator-associated pneumonia who do or do not develop acute respiratory distress syndrome. An observational study

E Barbeta, A Ceccato, A Artigas, M Ferrer… - Journal of clinical …, 2020 - mdpi.com
… that arises in patients on invasive mechanical ventilation. Its … These patients present with
longer duration of mechanical … mechanisms that can contribute to lung injury. Both pathogen-…

Incidence, risk factors, and effects on outcome of ventilator-associated pneumonia in patients with traumatic brain injury: analysis of a large, multicenter, prospective …

C Robba, P Rebora, E Banzato, EJA Wiegers… - Chest, 2020 - Elsevier
Patients with VAP had a longer duration of mechanical ventilation (median, 15 [IQR, 10-22]
days vs 8 [IQR, 5-14] days; P < .001) and ICU LOS (median, 20 [IQR, 14-29] days vs 13 [IQR, …

[HTML][HTML] Ventilator-associated pneumonia in patients on prolonged mechanical ventilation: description, risk factors for mortality, and performance of the SOFA score

SA Núñez, G Roveda, MS Zárate… - Jornal Brasileiro de …, 2021 - SciELO Brasil
… Comparison of the bacterial etiology of early-onset and late-onset ventilator-associated
pneumonia and chronic obstructive pulmonary disease: what is the current evidence? […

A ventilator-associated pneumonia prediction model in patients with acute respiratory distress syndrome

Z Wu, Y Liu, J Xu, J Xie, S Zhang… - Clinical Infectious …, 2020 - academic.oup.com
severe lung injury; hence, we compared these 2 markers of respiratory mechanics between
ARDS patients … Risk factors for late-onset ventilatorassociated pneumonia in trauma patients

Ventilator-associated pneumonia in neurocritically ill patients: insights from the ENIO international prospective observational study

D Battaglini, L Parodi, R Cinotti, K Asehnoune… - Respiratory …, 2023 - Springer
… all patients who lasted less than 48 h of invasive mechanical … [COPD = chronic obstructive
pulmonary disease, cardiovascular … predisposing to longer duration of mechanical ventilation, …

First stabilize and then gradually recruit: a paradigm shift in protective mechanical ventilation for acute lung injury

GF Nieman, DW Kaczka, PL Andrews, A Ghosh… - Journal of clinical …, 2023 - mdpi.com
… The exhalation duration is personalized and adaptive to individual respiratory mechanical
properties (ie, elastic recoil); and (ii) gradually recruiting collapsed lung tissue using an inflate …

… and predictors of in-hospital mortality in fibrotic interstitial lung disease with acute respiratory failure: a cohort analysis through the paradigm of acute respiratory …

MJ Martin, T Moua - Critical care medicine, 2020 - journals.lww.com
… Unadjusted ventilator-associated predictors included increased time to intubation (unit OR,
… and reduced duration of MV ( 6 ). Use of prone positioning has resulted in better survival for …