… gravitational gradient in regional lung tissue density… vertical gradient in perfusion from
gravitationally nondependent to dependent lung that is present across multiple postures (eg, prone…

… yield a corresponding wide range of regional lung density, perfusion and neutrophilic
112 … and a slight increase of nondependent perfusion was observed in prone animals. …

… in respiratory system compliance, regional lung ventilation, and perfusion despite significantly
lower lung … hypoxic pulmonary vasoconstriction, reducing intrapulmonary shunt and …

… position is predictive of improved outcome in acute respiratory distress syndrome. Crit …
Vertical gradients in regional lung density and perfusion in the supine human lung: the Slinky effect…

… terms, the lung can be thought of as a suspended ‘Slinky’ spring, … By modelling the lung as
a set of independent vertical columns, … Based on these reported gradients of lung density and …

… distress syndrome (ARDS) as well as the impact of prone … With respect to perfusion,
gravitational gradients drive perfusion … , an effect accentuated in the upright position. Local …

… The deformation of the lung as a result of its own weight (the Slinky … lungs, but exhibits a
vertical gradient; this is reduced on lying down, and the distribution is more uniform in a prone …

… between groups persisted after adjusting the regional blood flow by regional lung density …
no vertical gradient in perfusion in the lower or dependent part of the lung (dorsal in the supine …

… This degree of thinness also makes these membranes prone … the generated pressure gradient
and enters the lung. Note that … Figure 4.4: Lung = slinky. The weight pulling the coils open …

… of pulmonary perfusion within both human and pig lungs. The … from the supine to prone
position, both the gradient and … that a vertical gradient in ventilation exists in the human lung [90, …