Pyroptosis modulation by bacterial effector proteins

Q Chai, Z Lei, CH Liu - Seminars in Immunology, 2023 - Elsevier
… microbial ligands or pathogenic perturbations, and the … CASP4/5/11 is activated by cytosolic
lipopolysaccharide (LPS… of cell survival, hence conferring strong activity of caspase-8 …

[HTML][HTML] Non-antibiotic prevention and treatment against Acinetobacter baumannii infection: Are vaccines and adjuvants effective strategies?

Y Hu, X Zhang, S Deng, C Yue, X Jia… - Frontiers in Microbiology, 2023 - frontiersin.org
… in therapies have to be overcome by new strategies. … Except for the cell wall, the virulence
factor is also a good target, … is the main content of OMV, and the endotoxin activity of LPS also …

Human TLR4 and noncanonical inflammasome differ in their ability to respond to distinct lipid A variants

J Alexander-Floyd, AR Bass, EM Harberts, D Grubaugh… - bioRxiv, 2021 - biorxiv.org
… noncanonical inflammasome responses to LPS. IFNγ priming … pathogenic Gramnegative
bacterial infections. In this study, we used the BECC process to create a series of Yersinia pestis

Sneaky tactics: Ingenious immune evasion mechanisms of Bartonella

Y Xi, X Li, L Liu, F Xiu, X Yi, H Chen, X You - Virulence, 2024 - Taylor & Francis
… proteins and diverse lipopolysaccharide (LPS) structures that are not … Yersinia enterocolitica
adhesin A exerts anti-phagocytic … virulence factors mediating the entry of human pathogenic

One-step preparation of a self-assembled bioconjugate nanovaccine against Brucella

J Huang, Y Guo, S Yu, D Wang, S Li, J Wu, P Sun… - Virulence, 2023 - Taylor & Francis
… glycosylation system into the Yersinia enterocolitica serotype O:… To solve this problem, we
prepared a bioconjugate vaccine … antibodies levels against YeO9_52212 LPS, we then used a …

[HTML][HTML] Identification and Characterization of Key Host Pro-Inflammatory Cytokines During the Biphasic Disease Progression of Pneumonic Plague

HM Theriot - 2023 - search.proquest.com
… caused by the pathogen Yersinia pestis. The pneumonic … when removing the important
bacterial virulence factor Pla. Thus, … -dependent alteration in its lipopolysaccharide (LPS) lipid A …

Virulence evolution of bacterial species

R Elias, P Gomes, I Portugal, J Perdigão - Phylogenomics, 2024 - Elsevier
… includes the acquisition of virulence factors. Nevertheless, each … of the EM is covered by
lipopolysaccharides (LPS) that by … pseudotuberculosis, and Yersinia enterocolitica (both cause …

Possible drugs for the treatment of bacterial infections in the future: anti-virulence drugs

H Ogawara - The Journal of antibiotics, 2021 - nature.com
… Disarmed virulence factors make virulent pathogens … Several small molecules were reported
to inhibit Yersinia pestis type III … These compounds inhibited LPS-stimulated nitric oxide …

A novel mucosal vaccine platform for immunization against plague

C D'Arco - 2020 - touroscholar.touro.edu
… your support and the crazy good times at Captain Lawrence. … mutation in the pigmentation
locus of Yersinia pestis PRR … on the regulation of bacterium virulence factors are indicated at …

The evolution of a specialized, highly virulent fish pathogen through gene loss and acquisition of host-specific survival mechanisms

L Baseggio, O Rudenko, J Engelstädter… - Applied and …, 2022 - Am Soc Microbiol
virulence factors (8) and antibiotic resistance genes (9). Extensive research has focused on
Yersinia pestis… on chromosome 1 that encodes both lipopolysaccharide (LPS) O-antigen and …