… various behavioral testing methods for measuring orofacial pain … test orofacial pain by
assessing mouse biting function. In brief, a … software analyzes the behavior of voluntary biting [10]. …

… exhibit aggressive voluntary biting, a training phase is not needed. In this method, mice are
… (and often oscillating) pain, pain that is modified by jaw function (eg, chewing hard food, …

… is the most common form of orofacial pain. We recently found … Using bite force measurement,
we further demonstrated that … evaluated the functional contribution of CGRP to TMD pain. …

… blink and vibrissae movement as measures of facial nerve … that this functional deficit may be
more apparent in mice, with … , chewing, and swallowing behaviors during voluntary drinking …

… In brief, to measure pain facilitation by TSP, a noxious … function in the CNS associated with
affective dimension of … expression, are enhanced by repeated jaw openings in the rats [154,…

… to sliding irritation with normal chewing in the mice. A stepby-… is a particular consideration
in patients with orofacial pain (… Animals are free to voluntarily move their head away from the …

… in the sensory system and function in pathophysiological pain, including orofacial pain. …
a method of measuring bite force in mice as a clinically relevant metric of TMJD masticatory …

… voluntary from the mice. Following sucrose stimulus, a second pipet was introduced containing
a bitter solution. This solution was prepared by diluting three drops of anti-bite … oral pain …

… pain in 3-week-old male Wistar rats, direct blocking of the TRPV1 by antagonists (AMG9810)
reduced the effects of mechanical hyperalgesia in models of orofacial pain (… under voluntary …

… problem, we implemented a sheltering tube method to assess orofacial nociception in mice.
… Frey, acetone spray, and optogenetic tests in orofacial regions to investigate orofacial pain. …