… levels of fetal hemoglobin that does not polymerize, although … the decrease in the concentration
of the allosteric effector, 2,3-… 000 water molecules and Na + and Cl – ions (0.1 M NaCl). …

… Polymerization of deoxygenated sickle hemoglobin (HbS) … An ion exchange method was
used for separation of ATP … We hypothesized that mitapivat, an allosteric activator of PKR, would …

… will be varied are ionic strength and polymer chain length. … behaviour displayed when
oxygen binds to hemoglobin. The … states that the allosteric proteins are polymers (or oligomers) …

… the polymerisation of deoxyHbSS, induce an allosteric … main clinical symptoms are aplastic
and hemolytic anemia, … their abilities to neutralize free radical ions, chelate metals that form …

… levels, reducing the impact of HbS polymers, and of membrane events … The main alterations
in ion and water homeostasis are … hemoglobin oxygen affinity, which inhibits hemoglobin …

… The most basal allosteric effector in vertebrate hemoglobin is … with water to create bicarbonate
(HCO 3 − ) and hydrogen ions (… promote preservation by inducing polymerization [88,176]. …

… modified Hb suspensions (ie, polymerized Hb [5,6] Hb or … the effect of different concentrations
of PEG, metallic ions and … contrast to human Hb, which needs the allosteric effector 2,3-…

… of oxygen molecules to hemoglobin and complex processes … (positive allosteric effect)
or hinder (negative allosteric effect) … ) 200 ) polymer (20) to a superamphiphilic polymer by …

… is the allosteric binding of oxygen to hemoglobin in red blood … allosteric transitions (6), as
described in SI Appendix, Theory. We take the ionization of (weak) acid groups on the polymers …

… and application of hemoglobin and perfluorocarbon oxygen … and cross-linked with polymers
and protective enzymes. It not … binding of allosteric effectors such as hydrogen ions, carbon …