… and application of hemoglobin and perfluorocarbon oxygen … and cross-linked with polymers
and protective enzymes. It not … binding of allosteric effectors such as hydrogen ions, carbon …

… the activation effect of metal ions on Hb was investigated. … systems were incubated in a
thermostat water bath at 25 C for 3 … with ultrapure water 5 times, and stored in ultrapure water at 4 …

… The allosteric effect, described as biological enzymes’ … are created through the templation
effect of halide ions in a library of … of the enzyme creating an allosteric effect, which is one of …

… The disease is characterized by polymerization of HbS and sickling of red blood … the
hemoglobin allosteric effector, RSR-13 (aka Efaproxiral) (Figure 2), which binds to the central water …

… of oxygen molecules to hemoglobin and complex processes … (positive allosteric effect)
or hinder (negative allosteric effect) … ) 200 ) polymer (20) to a superamphiphilic polymer by …

… the polymerisation of deoxyHbSS, induce an allosteric … main clinical symptoms are aplastic
and hemolytic anemia, … their abilities to neutralize free radical ions, chelate metals that form …

… in the human body, the allosteric effect has a Hill coefficient … is the toxic side effects caused
by by-products such as metal ions, … In contrast, the co-encapsulated polymers could affect the …

… and sickle haemoglobin (HbS) polymer formation with no adverse effect on cellular water or
ionic … Thus, vanillin or its derivatives can be designed and tested for allosteric modulation in …

… –polymerization and nucleation–conversion–polymerization … ); 2,3-DPG is an allosteric
effector found in erythrocytes that … , water–water interactions, produce a small net effect on the …

… is the allosteric binding of oxygen to hemoglobin in red blood … allosteric transitions (6), as
described in SI Appendix, Theory. We take the ionization of (weak) acid groups on the polymers …