The genetics of kidney stone disease and nephrocalcinosis

P Singh, PC Harris, DJ Sas, JC Lieske - Nature Reviews Nephrology, 2022 - nature.com
… risk of chronic kidney disease (CKD) and kidney failure 13,… In this Review, we briefly discuss
kidney stone pathogenesis, … For higher risk groups, such as patients with cystinuria, water

Uremic toxins in the progression of chronic kidney disease and cardiovascular disease: mechanisms and therapeutic targets

YJ Lim, NA Sidor, NC Tonial, A Che, BL Urquhart - Toxins, 2021 - mdpi.com
… in CKD patients as a result of decreased kidney function [7]. … to investigate the efficacy
of dietary modulation in kidney … of inflammation in the Chronic Renal Insufficiency Cohort (CRIC…

Genome-wide association studies of CKD and related traits

A Tin, A Köttgen - Clinical Journal of the American Society of …, 2020 - journals.lww.com
… these recent GWAS of CKD and kidney function–related traits, … Investigations of kidney
function genetics have also started … of Diseases–coded chronic renal failure, glomerular diseases

The role of mitochondria in acute kidney injury and chronic kidney disease and its therapeutic potential

X Zhang, E Agborbesong, X Li - International journal of molecular …, 2021 - mdpi.com
… to the pathogenesis of different forms of kidney diseases, … minor loss of kidney function to
complete kidney failure and can … inhibitors application in CKD needs further investigation to be …

Onconephrology: the intersections between the kidney and cancer

MH Rosner, KD Jhaveri, BA McMahon… - CA: a cancer journal …, 2021 - Wiley Online Library
… A study in France investigated the outcomes of patients who … of estimating kidney function is
preferred in patients with cancer… For example, VEGF pathway inhibitors are another cause of …

… on major adverse kidney and cardiovascular events in patients with diabetic and non-diabetic chronic kidney disease: a prespecified analysis from the DAPA-CKD …

DC Wheeler, BV Stefánsson, N Jongs… - The lancet Diabetes & …, 2021 - thelancet.com
… risk of kidney failure and heart failure in patients with chronic … We aimed to investigate the
effects of dapagliflozin on kidney… to underlying cause of chronic kidney disease, reported as …

Chronic kidney disease and cerebrovascular disease: consensus and guidance from a KDIGO controversies conference

DM Kelly, Z Ademi, W Doehner, GYH Lip, P Mark… - Stroke, 2021 - Am Heart Assoc
… different to clot formed where renal function is normal; this may explain why patients with …
stroke from cause to treatment and rehabilitation. Further investigations specifically evaluating …

The role of disturbed Mg homeostasis in chronic kidney disease comorbidities

C Rodelo-Haad, MV Pendón-Ruiz de Mier… - Frontiers in cell and …, 2020 - frontiersin.org
… study, the authors investigated whether there were changes … higher in patients who did not
recover kidney function. These … due to the reduced renal function; for this reason, more clinical …

[HTML][HTML] Impaired muscle mitochondrial energetics is associated with uremic metabolite accumulation in chronic kidney disease

T Thome, RA Kumar, SK Burke, RB Khattri, ZR Salyers… - JCI insight, 2021 - ncbi.nlm.nih.gov
… directly link kidney function to skeletal muscle health in CKD. … -dihydroxyadenine in renal
tubules that cause kidney damage. … To date, much of the CKD literature examining the basis for …

Genetic testing in the diagnosis of chronic kidney disease: recommendations for clinical practice

N Knoers, C Antignac, C Bergmann… - Nephrology Dialysis …, 2022 - academic.oup.com
cause of the disease. In studies examining the diagnostic yield of MPS-based testing in …
The results of laboratory tests (eg kidney function), renal imaging and/or a renal biopsy and …